The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 62: U6 small nuclear RNA (adenine-(43)-N(6))-methyltra...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
U6 snRNA 3'-end binding GO:0030629
Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA).
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
U6 snRNA (adenine-(43)-N(6))-methyltransferase activity GO:0120048
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
MRNA (N6-adenosine)-methyltransferase activity GO:0001734
Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.
4 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS)
MRNA (N6-adenosine)-methyltransferase activity GO:0001734
Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.
2 Q86W50 (/IDA) Q9CQG2 (/IDA)
MRNA (N6-adenosine)-methyltransferase activity GO:0001734
Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.
1 Q9CQG2 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q86W50 (/HDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q86W50 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9CQG2 (/ISO)
U6 snRNA 3'-end binding GO:0030629
Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA).
1 Q86W50 (/IDA)
U6 snRNA 3'-end binding GO:0030629
Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA).
1 Q9CQG2 (/ISO)
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
1 Q86W50 (/IDA)
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
1 Q9CQG2 (/ISO)
U6 snRNA (adenine-(43)-N(6))-methyltransferase activity GO:0120048
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA
1 Q86W50 (/IDA)
U6 snRNA (adenine-(43)-N(6))-methyltransferase activity GO:0120048
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA
1 Q9CQG2 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q86W50 (/ISS)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
Regulation of mRNA splicing, via spliceosome GO:0048024
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
MRNA destabilization GO:0061157
Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q86W50 (/ISS)
SnRNA (adenine-N6)-methylation GO:0120049
The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
4 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
4 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
2 Q86W50 (/IMP) Q9CQG2 (/IMP)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
2 Q86W50 (/IDA) Q9CQG2 (/IDA)
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
1 Q9CQG2 (/IDA)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
1 Q9CQG2 (/IDA)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q86W50 (/IDA)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q9CQG2 (/ISO)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
1 Q9CQG2 (/ISO)
Regulation of mRNA splicing, via spliceosome GO:0048024
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
1 Q86W50 (/IDA)
MRNA destabilization GO:0061157
Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.
1 Q9CQG2 (/IDA)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
1 Q86W50 (/IDA)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
1 Q9CQG2 (/IMP)
MRNA methylation GO:0080009
The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
1 Q9CQG2 (/ISO)
SnRNA (adenine-N6)-methylation GO:0120049
The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.
1 Q86W50 (/IDA)
SnRNA (adenine-N6)-methylation GO:0120049
The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.
1 Q9CQG2 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q5ZIA0 (/ISS) Q6DC64 (/ISS) Q6GR37 (/ISS) Q6GR37 (/ISS) Q9CQG2 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q86W50 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9CQG2 (/ISO)
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