The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Malic enzyme, N-terminal domain
".
FunFam 3: NADP-dependent malic enzyme
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
18 |
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
(8 more) |
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
18 |
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
P76558 (/IMP)
(8 more) |
|
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
|
18 |
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
P76558 (/IDA)
(8 more) |
|
Malate dehydrogenase activity GO:0016615
Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
|
16 |
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
Q74AP4 (/ISS)
Q8E9Z2 (/ISS)
Q9KNQ0 (/ISS)
Q9KNQ0 (/ISS)
Q9KNQ0 (/ISS)
Q9KNQ0 (/ISS)
(6 more) |
|
Malic enzyme activity GO:0004470
Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
|
7 | Q2GHT3 (/ISS) Q2GLS5 (/ISS) Q2GLS5 (/ISS) Q2GLS5 (/ISS) Q2GLS5 (/ISS) Q2GLS5 (/ISS) Q5LPB6 (/ISS) |
|
Mannan binding GO:2001065
Interacting selectively and non-covalently with mannan.
|
2 | Q9CGB2 (/IDA) Q9CGB2 (/IDA) |
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
1 | Q5LWG9 (/ISS) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
24 |
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
A0A0F7RME4 (/ISS)
Q2GHT3 (/ISS)
Q2GLS5 (/ISS)
Q2GLS5 (/ISS)
Q2GLS5 (/ISS)
Q2GLS5 (/ISS)
Q2GLS5 (/ISS)
(14 more) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
18 |
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
P76558 (/HDA)
(8 more) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q9CGB2 (/IDA) Q9CGB2 (/IDA) |