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CATH Superfamily 3.40.50.10380

Malic enzyme, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Malic enzyme, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: NADP-dependent malic enzyme

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). [EC: 1.1.1.40]
(1) (S)-malate + NADP(+) = pyruvate + CO(2) + NADPH. (2) Oxaloacetate = pyruvate + CO(2).
  • The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39.
 485 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9 A0A069FGX9
(475 more...)