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CATH Superfamily 3.40.50.1010

5'-nuclease

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
5'-nuclease
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 85: Exonuclease

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Exodeoxyribonuclease (lambda-induced). [EC: 3.1.11.3]
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
  • Preference for double-stranded DNA.
  • Does not attack single-strand breaks.
  • Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV.
  • Formerly EC 3.1.4.28.
 13 P00638 P00638 P20321 P20321 P20321 Q6WYP0 Q6WYP0 Q778K3 Q778K3 Q778K3
(3 more...)