The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"HAD superfamily/HAD-like
".
FunFam 20: Probable cation-transporting P-type ATPase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cadmium transmembrane transporter activity, phosphorylative mechanism GO:0008551
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out).
|
10 | P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) |
Cobalt ion transmembrane transporter activity GO:0015087
Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Lead ion transmembrane transporter activity GO:0015094
Enables the transfer of lead (Pb) ions from one side of a membrane to the other.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Nickel cation transmembrane transporter activity GO:0015099
Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Zinc transmembrane transporter activity, phosphorylative mechanism GO:0016463
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).
|
10 | P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
10 | P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) P37617 (/ISA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O64474 (/IPI) O64474 (/IPI) O64474 (/IPI) P74512 (/IPI) P74512 (/IPI) |
Copper ion transmembrane transporter activity GO:0005375
Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
|
2 | B9DFX7 (/IMP) Q9SZC9 (/IMP) |
ATPase-coupled zinc transmembrane transporter activity GO:0015633
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).
|
1 | Q9M3H5 (/IDA) |
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
|
1 | Q9SZC9 (/IDA) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q9M3H5 (/IMP) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
13 |
Q9KS24 (/ISS)
Q9KS24 (/ISS)
Q9KS24 (/ISS)
Q9KS24 (/ISS)
Q9KS24 (/ISS)
Q9KS24 (/ISS)
Q9KT72 (/ISS)
Q9KT72 (/ISS)
Q9KT72 (/ISS)
Q9KT72 (/ISS)
(3 more) |
Zinc ion transport GO:0006829
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
13 |
O64474 (/IMP)
O64474 (/IMP)
O64474 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
(3 more) |
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
13 |
O64474 (/IMP)
O64474 (/IMP)
O64474 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
P37617 (/IMP)
(3 more) |
Cobalt ion transport GO:0006824
The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Detoxification of zinc ion GO:0010312
Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Lead ion transport GO:0015692
The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
10 | P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) P37617 (/IMP) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
8 | P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) P9WPS7 (/IDA) |
Zinc ion homeostasis GO:0055069
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
4 | O64474 (/IGI) O64474 (/IGI) O64474 (/IGI) Q9SZW4 (/IGI) |
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
|
3 | O64474 (/IMP) O64474 (/IMP) O64474 (/IMP) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
3 | O64474 (/IMP) O64474 (/IMP) O64474 (/IMP) |
Cadmium ion transport GO:0015691
The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | O64474 (/IMP) O64474 (/IMP) O64474 (/IMP) |
Metal ion transport GO:0030001
The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | O64474 (/IMP) O64474 (/IMP) O64474 (/IMP) |
Response to cobalt ion GO:0032025
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
|
3 | O64474 (/IMP) O64474 (/IMP) O64474 (/IMP) |
Copper ion import GO:0015677
The directed movement of copper ions into a cell or organelle.
|
2 | P74512 (/TAS) P74512 (/TAS) |
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | B9DFX7 (/IMP) |
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
|
1 | Q9M3H5 (/IMP) |
Response to light intensity GO:0009642
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
|
1 | Q9M3H5 (/IMP) |
Photosynthetic electron transport chain GO:0009767
A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.
|
1 | Q9SZC9 (/IMP) |
Copper ion transmembrane transport GO:0035434
The directed movement of copper cation across a membrane.
|
1 | Q9SZC9 (/IMP) |
Zinc ion homeostasis GO:0055069
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
1 | Q9M3H5 (/IMP) |
Copper ion homeostasis GO:0055070
Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
|
1 | Q9SZC9 (/IDA) |
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
|
1 | P0CW78 (/IMP) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
29 |
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPS7 (/HDA)
P9WPT3 (/HDA)
P9WPT3 (/HDA)
(19 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
14 |
O64474 (/IDA)
O64474 (/IDA)
O64474 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
P37617 (/IDA)
(4 more) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
10 | P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) P9WPT5 (/IGI) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
10 | P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) P37617 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
8 | P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) P9WPS7 (/HDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | P9WPU1 (/HDA) P9WPU1 (/HDA) P9WPU1 (/HDA) P9WPU1 (/HDA) |
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
4 | P9WPU1 (/HDA) P9WPU1 (/HDA) P9WPU1 (/HDA) P9WPU1 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P9WPT9 (/HDA) P9WPT9 (/HDA) P9WPT9 (/HDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | O64474 (/TAS) O64474 (/TAS) O64474 (/TAS) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
3 | O64474 (/IDA) O64474 (/IDA) O64474 (/IDA) |
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
2 | Q9M3H5 (/IDA) Q9SZC9 (/IDA) |
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
|
2 | Q9M3H5 (/IDA) Q9SZC9 (/IDA) |
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
|
2 | Q9M3H5 (/IDA) Q9SZC9 (/IDA) |
Chloroplast thylakoid membrane GO:0009535
The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
|
1 | B9DFX7 (/IDA) |
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
1 | Q9SZC9 (/IDA) |