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CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: Probable cation-transporting P-type ATPase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cadmium-exporting ATPase. [EC: 3.6.3.3]
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
 449 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0
(439 more...)
P-type Zn(2+) transporter. [EC: 7.2.2.12]
ATP + H(2)O + Zn(2+)(Side 1) = ADP + phosphate + Zn(2+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn(2+) and the related cations Cd(2+) and Pb(2+).
  • Formerly EC 3.6.3.5.
 446 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0 A0A024KYB0
(436 more...)
P-type Cu(+) transporter. [EC: 7.2.2.8]
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion.
  • Formerly EC 3.6.3.54.
 17 A0A045HSZ7 A0A045HSZ7 A0A045HSZ7 A0A045HSZ7 A5TYG5 A5TYG5 A5TYG5 A5TYG5 P9WPU0 P9WPU0
(7 more...)
P-type Cu(2+) transporter. [EC: 7.2.2.9]
ATP + H(2)O + Cu(2+)(Side 1) = ADP + phosphate + Cu(2+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.
  • Formerly EC 3.6.3.4.
 1 B9DFX7