The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: Ketohexokinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ketohexokinase activity GO:0004454
Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
4 P50053 (/IDA) P50053 (/IDA) P97328 (/IDA) Q02974 (/IDA)
Ketohexokinase activity GO:0004454
Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
3 P50053 (/TAS) P50053 (/TAS) Q02974 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P50053 (/IPI) P50053 (/IPI)
Ketohexokinase activity GO:0004454
Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
1 P97328 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
2 P50053 (/TAS) P50053 (/TAS)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q02974 (/IDA)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 P97328 (/IMP)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 P97328 (/ISO)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
1 Q02974 (/IDA)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
1 P97328 (/ISO)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 Q02974 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P97328 (/ISO)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 Q02974 (/IEP)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
1 Q02974 (/IDA)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
1 P97328 (/ISO)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
1 Q02974 (/TAS)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 Q02974 (/IDA)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P97328 (/ISO)
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
1 P97328 (/IC)
Glycolytic process through fructose-1-phosphate GO:0061625
The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.
1 P97328 (/IC)
Regulation of glycogen metabolic process GO:0070873
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
1 P97328 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P50053 (/IDA) P50053 (/IDA) P97328 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P50053 (/TAS) P50053 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P50053 (/HDA) P50053 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P97328 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P97328 (/ISO)
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