The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: tRNA(His) guanylyltransferase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA guanylyltransferase activity GO:0008193
Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.
6 F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4ISV6 (/TAS) F4ISV6 (/TAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
6 F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4IRQ5 (/TAS) F4ISV6 (/TAS) F4ISV6 (/TAS)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
4 F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
4 F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
4 F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP) F4IRQ5 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 F4IRQ5 (/IDA) F4IRQ5 (/IDA) F4IRQ5 (/IDA) F4IRQ5 (/IDA) F4ISV6 (/IDA) F4ISV6 (/IDA)