The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 153: Bifunctional RNase H/acid phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA-DNA hybrid ribonuclease activity GO:0004523
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)
Double-stranded RNA-specific ribonuclease activity GO:0032296
Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)
Alpha-ribazole phosphatase activity GO:0043755
Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)
DNA/RNA hybrid binding GO:0071667
Interacting selectively and non-covalently with a RNA/DNA hybrid.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)
Cobalamin biosynthetic process GO:0009236
The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
10 P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA) P9WLH5 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.