View in Gene3D

CATH Superfamily 3.30.420.10

Ribonuclease H-like superfamily/Ribonuclease H

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 153: Bifunctional RNase H/acid phosphatase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosylcobalamin/alpha-ribazole phosphatase. [EC: 3.1.3.73]
(1) Adenosylcobalamin 5'-phosphate + H(2)O = coenzyme B12 + phosphate. (2) Alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.
  • This enzyme catalyzes the last step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, characterized in Salmonella enterica.
  • It also participates in a salvage pathway that recycles cobinamide into adenosylcobalamin.
 110 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5
(100 more...)
Ribonuclease H. [EC: 3.1.26.4]
Endonucleolytic cleavage to 5'-phosphomonoester.
  • Acts on RNA-DNA hybrids.
 110 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5 A0A045IWC5
(100 more...)