The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: 4-coumarate--CoA ligase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
CoA-ligase activity GO:0016405
Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.
12 A1Z8Z9 (/TAS) O45873 (/TAS) Q9VDU0 (/TAS) Q9VDU1 (/TAS) Q9VDU2 (/TAS) Q9VDU3 (/TAS) Q9VDU4 (/TAS) Q9VGC5 (/TAS) Q9VRQ4 (/TAS) Q9W171 (/TAS)
(2 more)
Fatty acid ligase activity GO:0015645
Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.
11 A1Z8Z9 (/TAS) Q9VDU0 (/TAS) Q9VDU1 (/TAS) Q9VDU2 (/TAS) Q9VDU3 (/TAS) Q9VDU4 (/TAS) Q9VGC5 (/TAS) Q9VRQ4 (/TAS) Q9W171 (/TAS) Q9W2R1 (/TAS)
(1 more)
Oxalate-CoA ligase activity GO:0050203
Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.
9 P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) Q9SMT7 (/IDA) Q9SMT7 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
7 P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA)
4-coumarate-CoA ligase activity GO:0016207
Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
7 Q42524 (/IDA) Q42524 (/IDA) Q42524 (/IDA) Q9LU36 (/IDA) Q9S725 (/IDA) Q9S725 (/IDA) Q9S777 (/IDA)
Oxalate-CoA ligase activity GO:0050203
Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.
7 P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP)
Fatty-acyl-CoA synthase activity GO:0004321
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
2 Q84P23 (/IDA) Q9M0X9 (/IDA)
Long-chain fatty acid-CoA ligase activity GO:0004467
Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
2 Q9LQ12 (/IDA) Q9VXZ8 (/IDA)
Phenylacetate-CoA ligase activity GO:0047475
Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA.
2 D3GE78 (/IMP) D3GE78 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9LQ12 (/IPI)
4-coumarate-CoA ligase activity GO:0016207
Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
1 Q5LVA1 (/ISS)
CoA-ligase activity GO:0016405
Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.
1 Q84P24 (/IDA)
Acid-thiol ligase activity GO:0016878
Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
1 O74976 (/ISM)
Medium-chain fatty acid-CoA ligase activity GO:0031956
Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12.
1 Q9LQ12 (/IDA)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
11 A1Z8Z9 (/TAS) Q9VDU0 (/TAS) Q9VDU1 (/TAS) Q9VDU2 (/TAS) Q9VDU3 (/TAS) Q9VDU4 (/TAS) Q9VGC5 (/TAS) Q9VRQ4 (/TAS) Q9W171 (/TAS) Q9W2R1 (/TAS)
(1 more)
Oxalate catabolic process GO:0033611
The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.
9 P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Oxalate catabolic process GO:0033611
The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.
7 P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP) P38137 (/IMP)
Phenylpropanoid metabolic process GO:0009698
The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.
6 Q42524 (/TAS) Q42524 (/TAS) Q42524 (/TAS) Q9S725 (/TAS) Q9S725 (/TAS) Q9S777 (/TAS)
Jasmonic acid biosynthetic process GO:0009695
The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.
2 Q84P23 (/IDA) Q9M0X9 (/IDA)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
2 Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Positive regulation of seed germination GO:0010030
Any process that activates or increase the rate of seed germination.
2 Q9SMT7 (/IMP) Q9SMT7 (/IMP)
Seed coat development GO:0010214
The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
2 Q9SMT7 (/IMP) Q9SMT7 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9SMT7 (/IEP) Q9SMT7 (/IEP)
Fatty-acyl-CoA biosynthetic process GO:0046949
The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
2 Q9LQ12 (/IDA) Q9VXZ8 (/IDA)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 Q9SMT7 (/IMP) Q9SMT7 (/IMP)
Long-chain fatty acid metabolic process GO:0001676
The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
1 Q9VXZ8 (/IDA)
Acetyl-CoA metabolic process GO:0006084
The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
1 O74976 (/ISM)
Ubiquinone biosynthetic process GO:0006744
The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
1 Q84P24 (/IMP)
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
1 O45873 (/IGI)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q84P21 (/IEP)
Jasmonic acid biosynthetic process GO:0009695
The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.
1 Q84P21 (/IMP)
Phenylpropanoid metabolic process GO:0009698
The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.
1 Q5LVA1 (/ISS)
Phenylpropanoid biosynthetic process GO:0009699
The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.
1 Q9LU36 (/IDA)
Pollen exine formation GO:0010584
The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.
1 Q9S777 (/IMP)
Triglyceride catabolic process GO:0019433
The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
1 Q9VXZ8 (/IDA)
Detection of mechanical stimulus involved in sensory perception of touch GO:0050976
The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
1 O45873 (/IGI)
Detection of mechanical stimulus involved in sensory perception of touch GO:0050976
The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
1 O45873 (/IMP)
Sporopollenin biosynthetic process GO:0080110
The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.
1 Q9LQ12 (/IMP)
Sporopollenin biosynthetic process GO:0080110
The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.
1 Q9LQ12 (/TAS)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P38137 (/HDA) P38137 (/HDA) P38137 (/HDA) P38137 (/HDA) P38137 (/HDA) P38137 (/HDA) P38137 (/HDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
7 P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA)
Peroxisomal matrix GO:0005782
The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.
7 P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA) P38137 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q42524 (/IDA) Q42524 (/IDA) Q42524 (/IDA) Q9LQ12 (/IDA) Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
4 Q84P21 (/IDA) Q84P23 (/IDA) Q84P24 (/IDA) Q9M0X9 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 Q9SMT7 (/IDA) Q9SMT7 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 O45873 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9VXZ8 (/IDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
1 O74976 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9LQ12 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O74976 (/HDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q54WL7 (/HDA)
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