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CATH Superfamily 3.30.300.30

ANL, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Acyl-coenzyme A synthetase ACSM5, mitochondrial

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Medium-chain acyl-CoA ligase. [EC: 6.2.1.2]
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium- chain acyl-CoA.
  • Acts on fatty acids from C(4) to C(11) and on the corresponding 3-hydroxy and 2,3- or 3,4-unsaturated acids.
  • The enzyme from the bacterium Pseudomonas putida also acts on 4-oxo and 4-hydroxy derivatives.
 24 A0A088E5G6 A0A088E5G6 A0A2J8S1P2 A0A2J8S1P2 A4YDT1 A4YDT1 O70490 P0C7M7 Q08AH1 Q08AH3
(14 more...)
Acetate--CoA ligase. [EC: 6.2.1.1]
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
  • Also acts on propanoate and propenoate.
 4 A0A088E5G6 A0A088E5G6 A4YDT1 A4YDT1
4-hydroxybutyrate--CoA ligase (AMP-forming). [EC: 6.2.1.40]
ATP + 4-hydroxybutanoate + CoA = AMP + diphosphate + 4-hydroxybutanoyl- CoA.
  • Isolated from the archaeon Metallosphaera sedula.
  • Involved in the 3-hydroxypropanoate/4-hydroxybutanoate cycle.
  • Cf. EC 6.2.1.56.
 4 A0A088E5G6 A0A088E5G6 A4YDT1 A4YDT1
Propionate--CoA ligase. [EC: 6.2.1.17]
ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.
  • Propenoate can act instead of propanoate.
  • Not identical with EC 6.2.1.1 or EC 6.2.1.2.
 4 A0A088E5G6 A0A088E5G6 A4YDT1 A4YDT1
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