The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Adenosine deaminase RNA-specific B2 (inactive)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 17 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 P51400 (/ISS) Q90VV7 (/ISS) Q90VY9 (/ISS) Q91ZS8 (/ISS)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
4 P51400 (/ISS) Q90VV7 (/ISS) Q90VY9 (/ISS) Q91ZS8 (/ISS)
Double-stranded RNA adenosine deaminase activity GO:0003726
Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
4 P51400 (/ISS) Q90VV7 (/ISS) Q90VY9 (/ISS) Q91ZS8 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 P78563 (/HDA) Q9NS39 (/HDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P51400 (/IPI) P78563 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 P51400 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q91ZS8 (/ISO)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 P51400 (/IDA)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 Q91ZS8 (/ISO)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 Q9NS39 (/TAS)
Double-stranded RNA adenosine deaminase activity GO:0003726
Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
1 P51400 (/IDA)
Double-stranded RNA adenosine deaminase activity GO:0003726
Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
1 Q91ZS8 (/ISO)
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
1 Q9NS39 (/TAS)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 P78563 (/TAS)
Adenosine deaminase activity GO:0004000
Catalysis of the reaction: adenosine + H2O = inosine + NH3.
1 Q9NS39 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P51400 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q91ZS8 (/ISO)

There are 44 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
6 A5WUX0 (/IMP) A5WUX1 (/IMP) Q1RM21 (/IMP) Q504H1 (/IMP) Q90VY9 (/IMP) Q90VZ1 (/IMP)
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
6 A5WUX0 (/IMP) A5WUX1 (/IMP) Q1RM21 (/IMP) Q504H1 (/IMP) Q90VY9 (/IMP) Q90VZ1 (/IMP)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
6 A5WUX0 (/IMP) A5WUX1 (/IMP) Q1RM21 (/IMP) Q504H1 (/IMP) Q90VY9 (/IMP) Q90VZ1 (/IMP)
Anterior lateral line development GO:0048899
The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
6 A5WUX0 (/IMP) A5WUX1 (/IMP) Q1RM21 (/IMP) Q504H1 (/IMP) Q90VY9 (/IMP) Q90VZ1 (/IMP)
Posterior lateral line development GO:0048916
The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
6 A5WUX0 (/IMP) A5WUX1 (/IMP) Q1RM21 (/IMP) Q504H1 (/IMP) Q90VY9 (/IMP) Q90VZ1 (/IMP)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
4 P51400 (/ISS) Q90VV7 (/ISS) Q90VY9 (/ISS) Q91ZS8 (/ISS)
Adenosine to inosine editing GO:0006382
The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
3 P51400 (/IDA) P78563 (/IDA) Q91ZS8 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 P51400 (/ISS) Q91ZS8 (/ISS)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
2 P51400 (/ISS) Q91ZS8 (/ISS)
Negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387
The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.
2 P51400 (/ISS) Q91ZS8 (/ISS)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
2 P51400 (/ISS) Q91ZS8 (/ISS)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
2 P51400 (/ISS) Q91ZS8 (/ISS)
Adenosine to inosine editing GO:0006382
The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
1 Q91ZS8 (/IMP)
Adenosine to inosine editing GO:0006382
The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
1 Q91ZS8 (/ISO)
Adenosine to inosine editing GO:0006382
The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
1 P51400 (/ISS)
Adenosine to inosine editing GO:0006382
The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
1 P78563 (/TAS)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
1 Q91ZS8 (/ISO)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
1 Q91ZS8 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 P51400 (/IEP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P78563 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q91ZS8 (/ISO)
Base conversion or substitution editing GO:0016553
Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
1 P51400 (/IDA)
Base conversion or substitution editing GO:0016553
Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
1 Q91ZS8 (/ISO)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 P51400 (/IDA)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q91ZS8 (/ISO)
Facial nerve morphogenesis GO:0021610
The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
1 Q91ZS8 (/IMP)
Hypoglossal nerve morphogenesis GO:0021618
The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
1 Q91ZS8 (/IMP)
Spinal cord ventral commissure morphogenesis GO:0021965
The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.
1 Q91ZS8 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 P78563 (/IDA)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q91ZS8 (/ISO)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q91ZS8 (/IMP)
Negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387
The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.
1 P78563 (/IDA)
Negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387
The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.
1 Q91ZS8 (/ISO)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
1 P78563 (/IMP)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
1 Q91ZS8 (/ISO)
Positive regulation of mRNA processing GO:0050685
Any process that activates or increases the frequency, rate or extent of mRNA processing.
1 P51400 (/IDA)
Positive regulation of mRNA processing GO:0050685
Any process that activates or increases the frequency, rate or extent of mRNA processing.
1 Q91ZS8 (/ISO)
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
1 Q91ZS8 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 P78563 (/IDA)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q91ZS8 (/ISO)
Innervation GO:0060384
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
1 Q91ZS8 (/IMP)
Muscle tissue morphogenesis GO:0060415
The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.
1 Q91ZS8 (/IMP)
Motor behavior GO:0061744
The specific neuromuscular movement of a single organism in response to external or internal stimuli.
1 Q91ZS8 (/IMP)
Motor neuron apoptotic process GO:0097049
Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
1 Q91ZS8 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q90VV7 (/ISS) Q90VY9 (/ISS) Q91ZS8 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P51400 (/IDA) P78563 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 P51400 (/IDA) P78563 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q91ZS8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q91ZS8 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q91ZS8 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P78563 (/TAS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q91ZS8 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q91ZS8 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P78563 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q91ZS8 (/ISO)
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