The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 50: Peptidyl-tRNA hydrolase ICT1, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aminoacyl-tRNA hydrolase activity GO:0004045
Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
5 B5XAM2 (/ISS) B5XAM2 (/ISS) D2HD32 (/ISS) Q3T116 (/ISS) Q8R035 (/ISS)
Translation release factor activity, codon nonspecific GO:0016150
A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
5 B5XAM2 (/ISS) B5XAM2 (/ISS) D2HD32 (/ISS) Q3T116 (/ISS) Q8R035 (/ISS)
Aminoacyl-tRNA hydrolase activity GO:0004045
Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
1 Q14197 (/IDA)
Aminoacyl-tRNA hydrolase activity GO:0004045
Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
1 Q8R035 (/ISO)
Translation release factor activity, codon nonspecific GO:0016150
A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
1 Q14197 (/IDA)
Translation release factor activity, codon nonspecific GO:0016150
A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
1 Q8R035 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
5 B5XAM2 (/ISS) B5XAM2 (/ISS) D2HD32 (/ISS) Q3T116 (/ISS) Q8R035 (/ISS)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
1 Q14197 (/TAS)
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
1 Q14197 (/IDA)
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
1 Q8R035 (/ISO)
Mitochondrial translational termination GO:0070126
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
1 Q14197 (/TAS)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 B5XAM2 (/ISS) B5XAM2 (/ISS) D2HD32 (/ISS) Q3T116 (/ISS) Q8R035 (/ISS)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
5 B5XAM2 (/ISS) B5XAM2 (/ISS) D2HD32 (/ISS) Q3T116 (/ISS) Q8R035 (/ISS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 Q14197 (/TAS) Q3T116 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R035 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q14197 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R035 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q14197 (/TAS)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
1 Q14197 (/IDA)
Mitochondrial large ribosomal subunit GO:0005762
The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
1 Q8R035 (/ISO)
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