The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: Double-stranded RNA-binding protein 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
6 Q8GY79 (/IDA) Q8GY79 (/IDA) Q8H1D4 (/IDA) Q8H1D4 (/IDA) Q9SKN2 (/IDA) Q9SKN2 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 Q8GY79 (/IPI) Q8GY79 (/IPI) Q8H1D4 (/IPI) Q8H1D4 (/IPI) Q9SKN2 (/IPI) Q9SKN2 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Production of miRNAs involved in gene silencing by miRNA GO:0035196
Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.
4 Q8H1D4 (/IMP) Q8H1D4 (/IMP) Q9SKN2 (/IMP) Q9SKN2 (/IMP)
Production of siRNA involved in chromatin silencing by small RNA GO:0070919
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA.
4 Q8H1D4 (/IMP) Q8H1D4 (/IMP) Q9SKN2 (/IMP) Q9SKN2 (/IMP)
Production of ta-siRNAs involved in RNA interference GO:0010267
Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs.
2 Q8H1D4 (/IMP) Q8H1D4 (/IMP)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
2 Q8H1D4 (/IMP) Q8H1D4 (/IMP)
Viral gene silencing in virus induced gene silencing GO:0060145
The posttranscriptional gene silencing of viral genes after viral infection.
2 Q8H1D4 (/IMP) Q8H1D4 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8H1D4 (/IDA) Q8H1D4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9SKN2 (/IDA) Q9SKN2 (/IDA)
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