The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 101: Loquacious, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
6 M9MRT5 (/ISS) Q4TZM6 (/ISS) Q8IP72 (/ISS) Q9VJY9 (/ISS) X2J5X6 (/ISS) X2JAB1 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 M9MRT5 (/IPI) Q4TZM6 (/IPI) Q8IP72 (/IPI) Q9VJY9 (/IPI) X2J5X6 (/IPI) X2JAB1 (/IPI)
RISC complex binding GO:1905172
Interacting selectively and non-covalently with a RISC complex.
1 Q9VJY9 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
6 M9MRT5 (/IMP) Q4TZM6 (/IMP) Q8IP72 (/IMP) Q9VJY9 (/IMP) X2J5X6 (/IMP) X2JAB1 (/IMP)
Dosage compensation by hyperactivation of X chromosome GO:0009047
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
6 M9MRT5 (/IGI) Q4TZM6 (/IGI) Q8IP72 (/IGI) Q9VJY9 (/IGI) X2J5X6 (/IGI) X2JAB1 (/IGI)
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
6 M9MRT5 (/IMP) Q4TZM6 (/IMP) Q8IP72 (/IMP) Q9VJY9 (/IMP) X2J5X6 (/IMP) X2JAB1 (/IMP)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
6 M9MRT5 (/IMP) Q4TZM6 (/IMP) Q8IP72 (/IMP) Q9VJY9 (/IMP) X2J5X6 (/IMP) X2JAB1 (/IMP)
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
6 M9MRT5 (/IMP) Q4TZM6 (/IMP) Q8IP72 (/IMP) Q9VJY9 (/IMP) X2J5X6 (/IMP) X2JAB1 (/IMP)
Female germ-line stem cell asymmetric division GO:0048132
The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
6 M9MRT5 (/IMP) Q4TZM6 (/IMP) Q8IP72 (/IMP) Q9VJY9 (/IMP) X2J5X6 (/IMP) X2JAB1 (/IMP)
Production of small RNA involved in gene silencing by RNA GO:0070918
The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)
Regulation of production of small RNA involved in gene silencing by RNA GO:0070920
Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 M9MRT5 (/IDA) Q4TZM6 (/IDA) Q8IP72 (/IDA) Q9VJY9 (/IDA) X2J5X6 (/IDA) X2JAB1 (/IDA)
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