The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldolase class I
".
FunFam 138: NADPH dehydrogenase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
NADPH dehydrogenase activity GO:0003959
Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
|
5 | A0A1D8PPK1 (/IDA) P41816 (/IDA) P41816 (/IDA) Q03558 (/IDA) Q03558 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P41816 (/IPI) P41816 (/IPI) Q03558 (/IPI) Q03558 (/IPI) |
NADPH dehydrogenase activity GO:0003959
Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
|
2 | Q09670 (/ISM) Q09671 (/ISM) |
NADPH dehydrogenase activity GO:0003959
Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
|
1 | A0A1D8PPK1 (/IMP) |
NADPH dehydrogenase activity GO:0003959
Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
|
1 | A0A1D8PPK1 (/NAS) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
1 | A0A1D8PPK1 (/IDA) |
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
|
1 | A0A1D8PPK1 (/NAS) |
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
1 | A0A1D8PPK1 (/NAS) |
Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646
Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.
|
1 | Q4WZ70 (/TAS) |
Hormone binding GO:0042562
Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
|
1 | A0A1D8PPK1 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
4 | P41816 (/IMP) P41816 (/IMP) Q03558 (/IMP) Q03558 (/IMP) |
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
|
1 | A0A1D8PPK1 (/IDA) |
Ergot alkaloid biosynthetic process GO:0035837
The chemical reactions and pathways resulting in the formation of an ergot alkaloid.
|
1 | Q4WZ70 (/IDA) |
Cellular detoxification of aldehyde GO:0110095
Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
1 | Q09670 (/TAS) |
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
1 | Q09671 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q03558 (/HDA) Q03558 (/HDA) Q09670 (/HDA) Q09671 (/HDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q03558 (/HDA) Q03558 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q03558 (/HDA) Q03558 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q09670 (/HDA) Q09671 (/HDA) |
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
|
1 | A0A1D8PPK1 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | A0A1D8PPK1 (/IDA) |
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
|
1 | A0A1D8PPK1 (/IDA) |