The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADP-dependent oxidoreductase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: NAD(P)H-dependent D-xylose reductase xyl1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
D-xylose:NADP reductase activity GO:0032866
Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.
13 A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) P38715 (/IMP) P38715 (/IMP) P38715 (/IMP) P38715 (/IMP)
(3 more)
Alditol:NADP+ 1-oxidoreductase activity GO:0004032
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
8 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) Q6IMN8 (/IDA)
D-xylose:NADP reductase activity GO:0032866
Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.
8 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) W5RZ21 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
7 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA)
Alditol:NADP+ 1-oxidoreductase activity GO:0004032
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
7 Q5AWY7 (/RCA) Q5AWY7 (/RCA) Q5B0E4 (/RCA) Q5B0E4 (/RCA) Q5BCQ1 (/RCA) Q5BCQ1 (/RCA) Q5BGA7 (/RCA)
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
5 A2QVE5 (/IDA) A2QVE5 (/IDA) Q3ZFI7 (/IDA) Q3ZFI7 (/IDA) Q3ZFI7 (/IDA)
Glycerol dehydrogenase [NADP+] activity GO:0047956
Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.
4 Q5AWY7 (/RCA) Q5AWY7 (/RCA) Q5BCQ1 (/RCA) Q5BCQ1 (/RCA)
D-arabinose 1-dehydrogenase [NAD(P)+] activity GO:0045290
Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.
2 Q5B0E4 (/RCA) Q5B0E4 (/RCA)
Alcohol dehydrogenase (NADP+) activity GO:0008106
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
1 P27800 (/IDA)
Methylglyoxal reductase (NADH-dependent) activity GO:0019170
Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.
1 Q5BGA7 (/RCA)
Glyceraldehyde oxidoreductase activity GO:0043795
Catalysis of the reaction: D-glyceraldehyde + H2O + acceptor = D-glycerate + reduced acceptor.
1 Q55FL3 (/ISS)
D-xylulose reductase activity GO:0046526
Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH.
1 Q5BGA7 (/RCA)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arabinose catabolic process GO:0019568
The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.
15 A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2QVE5 (/IMP) A2QVE5 (/IMP) P38715 (/IMP) P38715 (/IMP)
(5 more)
D-xylose catabolic process GO:0042843
The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.
13 A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) A2Q8B5 (/IMP) P38715 (/IMP) P38715 (/IMP) P38715 (/IMP) P38715 (/IMP)
(3 more)
Galactose metabolic process GO:0006012
The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
7 Q5AWY7 (/RCA) Q5AWY7 (/RCA) Q5B0E4 (/RCA) Q5B0E4 (/RCA) Q5BCQ1 (/RCA) Q5BCQ1 (/RCA) Q5BGA7 (/RCA)
Galactose catabolic process GO:0019388
The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.
7 P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI)
Arabinose catabolic process GO:0019568
The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.
7 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA)
Tetrose metabolic process GO:0033347
The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
7 Q5AWY7 (/RCA) Q5AWY7 (/RCA) Q5B0E4 (/RCA) Q5B0E4 (/RCA) Q5BCQ1 (/RCA) Q5BCQ1 (/RCA) Q5BGA7 (/RCA)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
7 P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI) P38715 (/IGI)
D-xylose catabolic process GO:0042843
The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.
7 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
7 P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA) P38715 (/IDA)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
4 Q5AWY7 (/RCA) Q5AWY7 (/RCA) Q5BCQ1 (/RCA) Q5BCQ1 (/RCA)
D-galacturonate catabolic process GO:0019698
The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
3 Q3ZFI7 (/IDA) Q3ZFI7 (/IDA) Q3ZFI7 (/IDA)
Arabinose metabolic process GO:0019566
The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.
2 Q5B0E4 (/RCA) Q5B0E4 (/RCA)
Tetrose metabolic process GO:0033347
The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
2 A2QVE5 (/IDA) A2QVE5 (/IDA)
Xylulose metabolic process GO:0005997
The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
1 Q5BGA7 (/RCA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q6IMN8 (/IMP)
Methylglyoxal metabolic process GO:0009438
The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
1 Q5BGA7 (/RCA)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q6IMN8 (/HEP)
Negative regulation of aggregate size involved in sorocarp development GO:0031158
Any process that decreases the size of the aggregate formed during sorocarp formation.
1 Q6IMN8 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 Q6IMN8 (/IMP)
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
1 Q6IMN8 (/IMP)
Carbohydrate derivative metabolic process GO:1901135
The chemical reactions and pathways involving carbohydrate derivative.
1 Q55FL3 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
10 Q2UHY1 (/IDA) Q2UHY1 (/IDA) Q2UKD0 (/IDA) Q2UKD0 (/IDA) Q2UKD0 (/IDA) Q2UKD0 (/IDA) Q2UKD0 (/IDA) Q5AWY7 (/IDA) Q5AWY7 (/IDA) Q5BGA7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA) P38715 (/HDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 P27800 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q6IMN8 (/IDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q6IMN8 (/HDA)
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