The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"tricorn interacting facor f3 domain
".
FunFam 1: Leucyl-cystinyl aminopeptidase
There are 3 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Membrane alanyl aminopeptidase.
[EC: 3.4.11.2]
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
|
11 |
A0A024RC61
A0A024RC61
P15144
P15144
P15145
P15541
P15684
P79098
P79143
P79171 (1 more...) |
|
Cystinyl aminopeptidase.
[EC: 3.4.11.3]
Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half- cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.
|
3 | P97629 Q8C129 Q9UIQ6 |
|
Aminopeptidase Ey.
[EC: 3.4.11.20]
Differs from other aminopeptidases in broad specificity for amino acids in the P1 position and the ability to hydrolyze peptides of four or five residues that contain Pro in the P1' position.
|
1 | O57579 |
