The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cik1 suppressing-related protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q12421 (/IPI) Q12421 (/IPI) Q12421 (/IPI) Q12421 (/IPI) Q12421 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Autophagy of mitochondrion GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
5 Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
5 Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP)
Piecemeal microautophagy of the nucleus GO:0034727
Degradation of a cell nucleus by lysosomal microautophagy.
5 Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP)
Late nucleophagy GO:0044805
A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.
5 Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP) Q12421 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phagophore assembly site GO:0000407
Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
5 Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA) Q12421 (/HDA)
Atg1/ULK1 kinase complex GO:1990316
A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
5 Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA) Q12421 (/IDA)