The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 33: Trailer hitch, isoform C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 M9PCB7 (/IPI) M9PF14 (/IPI) M9PF20 (/IPI) M9PFB2 (/IPI) M9PFF9 (/IPI) M9PFG3 (/IPI) M9PI44 (/IPI) Q9C658 (/IPI) Q9HGL3 (/IPI) Q9VTZ0 (/IPI)
DEAD/H-box RNA helicase binding GO:0017151
Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
2 M9PF20 (/IPI) Q9VTZ0 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9HGL3 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q9C658 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9C658 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9FH77 (/ISS)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
8 M9PCB7 (/IMP) M9PF14 (/IMP) M9PF20 (/IMP) M9PFB2 (/IMP) M9PFF9 (/IMP) M9PFG3 (/IMP) M9PI44 (/IMP) Q9VTZ0 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
8 M9PCB7 (/IMP) M9PF14 (/IMP) M9PF20 (/IMP) M9PFB2 (/IMP) M9PFF9 (/IMP) M9PFG3 (/IMP) M9PI44 (/IMP) Q9VTZ0 (/IMP)
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
1 Q9VTZ0 (/IMP)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
1 M9PF14 (/IMP)
Positive regulation of cytoplasmic mRNA processing body assembly GO:0010606
Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
1 Q9C658 (/IMP)
Positive regulation of cytoplasmic mRNA processing body assembly GO:0010606
Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
1 Q9FH77 (/ISS)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q9C658 (/IMP)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q9FH77 (/ISS)
Deadenylation-independent decapping of nuclear-transcribed mRNA GO:0031087
Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.
1 Q9C658 (/IMP)
Deadenylation-independent decapping of nuclear-transcribed mRNA GO:0031087
Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.
1 Q9FH77 (/ISS)
Cytoplasmic mRNA processing body assembly GO:0033962
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
1 Q9C658 (/IMP)
Cytoplasmic mRNA processing body assembly GO:0033962
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
1 Q9HGL3 (/ISO)
Positive regulation of protein exit from endoplasmic reticulum GO:0070863
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
1 Q9VTZ0 (/IMP)
Negative regulation of cytoplasmic translational initiation GO:1904689
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.
1 Q9HGL3 (/ISO)
Positive regulation of determination of dorsal identity GO:2000017
Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.
1 Q9VTZ0 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 M9PCB7 (/HDA) M9PF14 (/HDA) M9PF20 (/HDA) M9PFB2 (/HDA) M9PFF9 (/HDA) M9PFG3 (/HDA) M9PI44 (/HDA) Q9VTZ0 (/HDA)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
8 M9PCB7 (/IDA) M9PF14 (/IDA) M9PF20 (/IDA) M9PFB2 (/IDA) M9PFF9 (/IDA) M9PFG3 (/IDA) M9PI44 (/IDA) Q9VTZ0 (/IDA)
Fusome GO:0045169
A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.
8 M9PCB7 (/IDA) M9PF14 (/IDA) M9PF20 (/IDA) M9PFB2 (/IDA) M9PFF9 (/IDA) M9PFG3 (/IDA) M9PI44 (/IDA) Q9VTZ0 (/IDA)
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
2 Q9C658 (/IDA) Q9VTZ0 (/IDA)
Messenger ribonucleoprotein complex GO:1990124
A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
2 M9PF20 (/IDA) Q9VTZ0 (/IDA)
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
1 Q9FH77 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9HGL3 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9C658 (/IDA)
Neuronal ribonucleoprotein granule GO:0071598
A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.
1 M9PF20 (/IDA)
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