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CATH Superfamily 2.30.30.100

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30: Bifunctional ligase/repressor BirA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial-type RNA polymerase regulatory region sequence-specific DNA binding GO:0000984
Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 22 P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA)
(12 more)
Biotin-[acetyl-CoA-carboxylase] ligase activity GO:0004077
Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).
 22 P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA)
(12 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 22 P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI) P06709 (/IPI)
(12 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
Biotin binding GO:0009374
Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
 22 P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA)
(12 more)
Biotin binding GO:0009374
Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
Biotin-[acetyl-CoA-carboxylase] ligase activity GO:0004077
Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).
 8 Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Biotin metabolic process GO:0006768
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
Biotin biosynthetic process GO:0009102
The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
Protein biotinylation GO:0009305
The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid.
 22 P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA)
(12 more)
Biotin biosynthetic process GO:0009102
The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
 8 Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS) Q9KV39 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
 22 P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA) P06709 (/IDA)
(12 more)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
 22 P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP) P06709 (/IMP)
(12 more)
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