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CATH Superfamily 2.30.110.10

Electron Transport, Fmn-binding Protein; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Electron Transport, Fmn-binding Protein; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: FMN reductase (NADH) RutF

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
FMN reductase (NADH). [EC: 1.5.1.42]
FMNH(2) + NAD(+) = FMN + NADH.
  • The enzyme often forms a two-component system with monooxygenases.
  • Unlike EC 1.5.1.38 and EC 1.5.1.39, this enzyme has a strong preference for NADH over NADPH, although some activity with the latter is observed.
  • While FMN is the preferred substrate, FAD can also be used with much lower activity.
 10148 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6 A0A023YVL6
(10138 more...)
Flavin reductase (NADH). [EC: 1.5.1.36]
Reduced flavin + NAD(+) = flavin + NADH.
  • The enzyme from Escherichia coli W catalyzes the reduction of free flavins by NADH.
  • The enzyme has similar affinity to FAD, FMN and riboflavin.
  • Activity with NADPH is more than 2 orders of magnitude lower than activity with NADH.
 3922 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0 A0A0D6GNH0
(3912 more...)
FAD reductase (NADH). [EC: 1.5.1.37]
FADH(2) + NAD(+) = FAD + NADH.
  • The enzyme from Burkholderia phenoliruptrix can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD.
  • Unlike EC 1.5.1.36, the enzyme can not reduce riboflavin.
  • The enzyme does not use NADPH as acceptor.
 50 A0A072ZDW9 A0A072ZDW9 A0A072ZDW9 A0A072ZDW9 A0A072ZDW9 A0A072ZDW9 A0A072ZDW9 A0A1G5GZZ6 A0A1G5GZZ6 A0A1G5GZZ6
(40 more...)