The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Terpene cyclase/mutase family member

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Beta-amyrin synthase activity GO:0042300
Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.
5 A8CDT2 (/IDA) P0C8Y0 (/IDA) Q8RWT0 (/IDA) Q9C5M3 (/IDA) Q9LRH7 (/IDA)
Lupeol synthase activity GO:0042299
Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.
4 A8CDT3 (/IDA) Q764T8 (/IDA) Q8W3Z2 (/IDA) Q9C5M3 (/IDA)
Intramolecular transferase activity GO:0016866
Catalysis of the transfer of a functional group from one position to another within a single molecule.
3 E2IUA7 (/IDA) E2IUA8 (/IDA) E2IUA9 (/IDA)
Oxidosqualene cyclase activity GO:0031559
Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
1 Q9SYN1 (/IDA)
Marneral synthase activity GO:0034074
Catalysis of the reaction: oxidosqualene = marneral.
1 Q9FJV8 (/IDA)
Arabidiol synthase activity GO:0034075
Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).
1 Q9FR95 (/IDA)
Lupeol synthase activity GO:0042299
Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.
1 Q9LVY2 (/ISS)
Lupeol synthase activity GO:0042299
Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.
1 Q9SYN1 (/TAS)
Alpha-amyrin synthase activity GO:0042561
Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin.
1 Q9LRH7 (/IDA)
Thalianol synthase activity GO:0051746
Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).
1 Q9FI37 (/IDA)
Baruol synthase activity GO:0080011
Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.
1 O23390 (/IDA)
Camelliol C synthase activity GO:0090438
Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C.
1 P0C8Y0 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Triterpenoid biosynthetic process GO:0016104
The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.
8 A8CDT2 (/IDA) A8CDT3 (/IDA) E2IUA7 (/IDA) E2IUA8 (/IDA) E2IUA9 (/IDA) Q8RWT0 (/IDA) Q9FJV8 (/IDA) Q9FR95 (/IDA)
Pentacyclic triterpenoid biosynthetic process GO:0019745
The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
3 Q764T8 (/IDA) Q8W3Z2 (/IDA) Q9LRH7 (/IDA)
Tricyclic triterpenoid biosynthetic process GO:0010263
The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.
2 Q9FI37 (/IDA) Q9FR95 (/IDA)
Tetracyclic triterpenoid biosynthetic process GO:0010686
The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
1 O23390 (/IDA)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
1 Q9FI37 (/IMP)
Thalianol metabolic process GO:0080003
The chemical reactions and pathways involving the triterpene thalianol.
1 Q9FI37 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9FJV8 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
1 Q9LVY2 (/IDA)
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