The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dbl homology (DH) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28: Puratrophin-1-like, isoform D

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5 M9PEF7 (/ISS) Q7KU87 (/ISS) Q7KU88 (/ISS) Q7KU89 (/ISS) Q86NW6 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
7 A0A2R8QD21 (/IMP) A0A2R8QLC3 (/IMP) A0A2R8QQC5 (/IMP) B3DH45 (/IMP) F1RDN8 (/IMP) Q6DN89 (/IMP) X1WBU3 (/IMP)
Mesoderm morphogenesis GO:0048332
The process in which the anatomical structures of the mesoderm are generated and organized.
7 A0A2R8QD21 (/IMP) A0A2R8QLC3 (/IMP) A0A2R8QQC5 (/IMP) B3DH45 (/IMP) F1RDN8 (/IMP) Q6DN89 (/IMP) X1WBU3 (/IMP)
Imaginal disc-derived leg morphogenesis GO:0007480
The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
5 M9PEF7 (/IMP) Q7KU87 (/IMP) Q7KU88 (/IMP) Q7KU89 (/IMP) Q86NW6 (/IMP)
Positive regulation of Rho protein signal transduction GO:0035025
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
5 M9PEF7 (/ISS) Q7KU87 (/ISS) Q7KU88 (/ISS) Q7KU89 (/ISS) Q86NW6 (/ISS)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
5 M9PEF7 (/IMP) Q7KU87 (/IMP) Q7KU88 (/IMP) Q7KU89 (/IMP) Q86NW6 (/IMP)
Regulation of locomotor rhythm GO:1904059
Any process that modulates the frequency, rate or extent of locomotor rhythm.
5 M9PEF7 (/IGI) Q7KU87 (/IGI) Q7KU88 (/IGI) Q7KU89 (/IGI) Q86NW6 (/IGI)
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
1 F8VPS6 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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