The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Dbl homology (DH) domain
".
FunFam 22: protein ECT2 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
12 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
Q9H8V3 (/IDA)
(2 more) |
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
|
12 |
A8JNN0 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
Q07139 (/IPI)
Q8IQ95 (/IPI)
Q8IQ96 (/IPI)
Q8IQ96 (/IPI)
Q8IQ97 (/IPI)
(2 more) |
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
11 |
A8JNN0 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
Q8IQ95 (/ISS)
Q8IQ96 (/ISS)
Q8IQ96 (/ISS)
Q8IQ97 (/ISS)
Q9U7D8 (/ISS)
(1 more) |
Semaphorin receptor binding GO:0030215
Interacting selectively and non-covalently with semaphorin receptors.
|
11 |
A8JNN0 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
D2NUE8 (/IPI)
Q8IQ95 (/IPI)
Q8IQ96 (/IPI)
Q8IQ96 (/IPI)
Q8IQ97 (/IPI)
Q9U7D8 (/IPI)
(1 more) |
Rac guanyl-nucleotide exchange factor activity GO:0030676
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
11 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
Q9U7D8 (/IDA)
(1 more) |
Phosphatidylinositol phosphate binding GO:1901981
Interacting selectively and non-covalently with phosphatidylinositol phosphate.
|
11 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
Q9U7D8 (/IDA)
(1 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q07139 (/IPI) Q9H8V3 (/IPI) |
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
1 | Q07139 (/ISO) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q9H8V3 (/IMP) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q07139 (/ISO) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q07139 (/ISS) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9H8V3 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q07139 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q07139 (/ISS) |
There are 72 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
12 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9H8V3 (/IMP)
(2 more) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
12 |
A8JNN0 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
D2NUE8 (/ISS)
Q07139 (/ISS)
Q8IQ95 (/ISS)
Q8IQ96 (/ISS)
Q8IQ96 (/ISS)
Q8IQ97 (/ISS)
(2 more) |
Actomyosin contractile ring assembly GO:0000915
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Actomyosin contractile ring assembly GO:0000915
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
11 |
A8JNN0 (/TAS)
D2NUE8 (/TAS)
D2NUE8 (/TAS)
D2NUE8 (/TAS)
D2NUE8 (/TAS)
Q8IQ95 (/TAS)
Q8IQ96 (/TAS)
Q8IQ96 (/TAS)
Q8IQ97 (/TAS)
Q9U7D8 (/TAS)
(1 more) |
Meiosis I cytokinesis GO:0007110
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Meiosis II cytokinesis GO:0007111
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Defasciculation of motor neuron axon GO:0007415
Separation of a motor axon away from a bundle of axons known as a fascicle.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Malpighian tubule morphogenesis GO:0007443
The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Mesoderm migration involved in gastrulation GO:0007509
The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Mesodermal cell migration GO:0008078
The orderly movement of mesodermal cells from one site to another.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Maintenance of protein location in cell GO:0032507
Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
11 |
A8JNN0 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
Q8IQ95 (/IGI)
Q8IQ96 (/IGI)
Q8IQ96 (/IGI)
Q8IQ97 (/IGI)
Q9U7D8 (/IGI)
(1 more) |
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
|
11 |
A8JNN0 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
D2NUE8 (/IGI)
Q8IQ95 (/IGI)
Q8IQ96 (/IGI)
Q8IQ96 (/IGI)
Q8IQ97 (/IGI)
Q9U7D8 (/IGI)
(1 more) |
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Mitotic actomyosin contractile ring assembly GO:1903475
Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
|
11 |
A8JNN0 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
D2NUE8 (/IMP)
Q8IQ95 (/IMP)
Q8IQ96 (/IMP)
Q8IQ96 (/IMP)
Q8IQ97 (/IMP)
Q9U7D8 (/IMP)
(1 more) |
Cytokinetic process GO:0032506
A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
|
6 | A0A0R4IKD5 (/IMP) A0A2R8Q1Z1 (/IMP) A0A2R8RJY1 (/IMP) F1QVS6 (/IMP) Q4V9L0 (/IMP) Q6DRB9 (/IMP) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | Q07139 (/ISO) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | Q07139 (/ISS) |
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
1 | Q07139 (/IDA) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | Q9H8V3 (/TAS) |
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | Q8IQ97 (/IMP) |
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q8IQ97 (/IMP) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
1 | Q9H8V3 (/IDA) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
1 | Q07139 (/ISO) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
1 | Q07139 (/ISS) |
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
1 | Q9H8V3 (/IDA) |
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
1 | Q9H8V3 (/IMP) |
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
1 | Q07139 (/ISO) |
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
1 | Q07139 (/ISS) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | Q8IQ97 (/IMP) |
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
|
1 | Q07139 (/IDA) |
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
|
1 | Q9H8V3 (/ISS) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9H8V3 (/IDA) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q07139 (/ISO) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q07139 (/ISS) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9H8V3 (/TAS) |
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
1 | Q9H8V3 (/HMP) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | Q9H8V3 (/IDA) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | Q9H8V3 (/IMP) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | Q07139 (/ISO) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q07139 (/IMP) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q9H8V3 (/ISS) |
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
|
1 | Q9H8V3 (/IDA) |
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
|
1 | Q07139 (/ISO) |
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
|
1 | Q07139 (/ISS) |
Regulation of small GTPase mediated signal transduction GO:0051056
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | Q9H8V3 (/TAS) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q9H8V3 (/IDA) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q07139 (/ISO) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q07139 (/ISS) |
Regulation of attachment of spindle microtubules to kinetochore GO:0051988
Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
|
1 | Q9H8V3 (/IMP) |
Regulation of attachment of spindle microtubules to kinetochore GO:0051988
Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
|
1 | Q07139 (/ISO) |
Regulation of attachment of spindle microtubules to kinetochore GO:0051988
Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
|
1 | Q07139 (/ISS) |
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | Q9H8V3 (/IDA) |
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | Q07139 (/ISO) |
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | Q07139 (/ISS) |
Bicellular tight junction assembly GO:0070830
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
|
1 | Q9H8V3 (/IMP) |
Bicellular tight junction assembly GO:0070830
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
|
1 | Q07139 (/ISO) |
Bicellular tight junction assembly GO:0070830
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
|
1 | Q07139 (/ISS) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q9H8V3 (/IDA) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q07139 (/ISO) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q07139 (/ISS) |
Cellular response to ionizing radiation GO:0071479
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | Q9H8V3 (/IDA) |
Cellular response to ionizing radiation GO:0071479
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | Q07139 (/ISO) |
Cellular response to ionizing radiation GO:0071479
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | Q07139 (/ISS) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q9H8V3 (/IDA) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q9H8V3 (/IMP) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q07139 (/ISO) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | Q07139 (/ISS) |
There are 28 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
13 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q07139 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
(3 more) |
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
|
12 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
Q9H8V3 (/IDA)
(2 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
A8JNN0 (/NAS)
D2NUE8 (/NAS)
D2NUE8 (/NAS)
D2NUE8 (/NAS)
D2NUE8 (/NAS)
Q8IQ95 (/NAS)
Q8IQ96 (/NAS)
Q8IQ96 (/NAS)
Q8IQ97 (/NAS)
Q9U7D8 (/NAS)
(1 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
11 |
A8JNN0 (/HDA)
D2NUE8 (/HDA)
D2NUE8 (/HDA)
D2NUE8 (/HDA)
D2NUE8 (/HDA)
Q8IQ95 (/HDA)
Q8IQ96 (/HDA)
Q8IQ96 (/HDA)
Q8IQ97 (/HDA)
Q9U7D8 (/HDA)
(1 more) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
11 |
A8JNN0 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
D2NUE8 (/IDA)
Q8IQ95 (/IDA)
Q8IQ96 (/IDA)
Q8IQ96 (/IDA)
Q8IQ97 (/IDA)
Q9U7D8 (/IDA)
(1 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q07139 (/IDA) Q9H8V3 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q07139 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q07139 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9H8V3 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q07139 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9H8V3 (/TAS) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q9H8V3 (/IDA) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q07139 (/ISO) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q07139 (/ISS) |
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
|
1 | Q9H8V3 (/IDA) |
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
|
1 | Q07139 (/ISO) |
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
|
1 | Q07139 (/ISS) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q9H8V3 (/IDA) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q07139 (/ISO) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q07139 (/ISS) |
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
|
1 | Q07139 (/ISO) |
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
|
1 | Q07139 (/ISS) |
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | Q9H8V3 (/IDA) |
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | Q07139 (/ISO) |
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | Q07139 (/ISS) |
Centralspindlin complex GO:0097149
A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
|
1 | Q9H8V3 (/IDA) |
Centralspindlin complex GO:0097149
A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
|
1 | Q07139 (/ISO) |
Centralspindlin complex GO:0097149
A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
|
1 | Q07139 (/ISS) |