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CATH Superfamily 1.20.58.1000

Metal-sensitive repressor, helix protomer

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metal-sensitive repressor, helix protomer
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Copper-sensing transcriptional repressor CsoR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 11 P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP)
(1 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 11 P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP)
(1 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 11 P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI) P9WP49 (/IPI)
(1 more)
Copper ion sensor activity GO:0097077
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to silver ion GO:0010272
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 11 P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP)
(1 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 11 P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP) P9WP49 (/IEP)
(1 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 11 P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA) P9WP49 (/HDA)
(1 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 11 P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP) P9WP49 (/EXP)
(1 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 11 P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA) P9WP49 (/IDA)
(1 more)