The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
6-Phosphogluconate Dehydrogenase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 6-phosphogluconate dehydrogenase, decarboxylating

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphogluconate dehydrogenase (decarboxylating) activity GO:0004616
Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
55 A0A0F7R7Y8 (/ISS) A0A0F7R7Y8 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS)
(45 more)
Phosphogluconate dehydrogenase (decarboxylating) activity GO:0004616
Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
9 P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) Q94KU2 (/IDA) Q9FWA3 (/IDA) Q9FWA3 (/IDA)
Phosphogluconate dehydrogenase (decarboxylating) activity GO:0004616
Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
6 P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
6 P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI) P00350 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q9FFR3 (/IPI) Q9FFR3 (/IPI) Q9FWA3 (/IPI) Q9FWA3 (/IPI) Q9SH69 (/IPI)
Phosphogluconate 2-dehydrogenase activity GO:0008114
Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.
3 Q9FFR3 (/IDA) Q9FFR3 (/IDA) Q9SH69 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
55 A0A0F7R7Y8 (/ISS) A0A0F7R7Y8 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS) P14062 (/ISS)
(45 more)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
10 Q2R480 (/IEP) Q9FWA3 (/IEP) Q9FWA3 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9SH69 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
7 Q2R480 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
7 Q2R480 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
7 Q2R480 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP) Q9LI00 (/IEP)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
6 P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA)
D-gluconate catabolic process GO:0046177
The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
6 P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP) P00350 (/IMP)
Pentose-phosphate shunt, oxidative branch GO:0009051
The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
3 Q9FFR3 (/IGI) Q9FFR3 (/IGI) Q9SH69 (/IGI)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2 Q9FFR3 (/IEP) Q9FFR3 (/IEP)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 Q9FFR3 (/IEP) Q9FFR3 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
2 Q9FFR3 (/IEP) Q9FFR3 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9FFR3 (/IEP) Q9FFR3 (/IEP)
Male-female gamete recognition during double fertilization forming a zygote and endosperm GO:0080173
The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.
2 Q9FWA3 (/IMP) Q9FWA3 (/IMP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 Q94KU2 (/IDA)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 O51509 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) P00350 (/IDA) Q9FFR3 (/IDA) Q9FFR3 (/IDA) Q9FWA3 (/IDA)
(2 more)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
5 Q9FFR3 (/IDA) Q9FFR3 (/IDA) Q9FWA3 (/IDA) Q9FWA3 (/IDA) Q9SH69 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 Q94KU2 (/IDA) Q9FFR3 (/IDA) Q9FFR3 (/IDA) Q9SH69 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
3 Q9FFR3 (/IDA) Q9FFR3 (/IDA) Q9SH69 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9FFR3 (/IDA) Q9FFR3 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 Q9FWA3 (/IDA) Q9FWA3 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 Q9FWA3 (/IPI) Q9FWA3 (/IPI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9FWA3 (/IPI) Q9FWA3 (/IPI)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9FFR3 (/IDA) Q9FFR3 (/IDA)
P4 peroxisome GO:0019822
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.
2 Q9FWA3 (/IDA) Q9FWA3 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9SH69 (/IDA)