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CATH Superfamily 1.20.5.320

6-Phosphogluconate Dehydrogenase, domain 3

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
6-Phosphogluconate Dehydrogenase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 6-phosphogluconate dehydrogenase, decarboxylating

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). [EC: 1.1.1.44]
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.
  • Highly specific for NADP(+).
  • Cf. EC 1.1.1.343.
 1325 A0A069Y009 A0A069Y009 A0A069Y009 A0A069Y009 A0A069Y009 A0A069Y009 A0A085C7B2 A0A085C7B2 A0A085C7B2 A0A085C7B2
(1315 more...)
Phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). [EC: 1.1.1.343]
6-phospho-D-gluconate + NAD(+) = D-ribulose 5-phosphate + CO(2) + NADH.
  • Highly specific for NAD(+).
  • The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.
  • In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway.
  • Cf. EC 1.1.1.44.
 25 A0A162R5E9 A0A162R5E9 A0A162R5E9 A0A162R5E9 A0A162R5E9 A0A1B2B8K1 A0A1B2B8K1 A0A1B2B8K1 A0A1B2B8K1 A0A1B2B8K1
(15 more...)