The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Fumarase/aspartase (Central domain)
".
FunFam 3: Histidine ammonia-lyase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
8 | Q54JI7 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) |
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
6 | Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) |
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
3 | P21213 (/IDA) P35492 (/IDA) P35492 (/IDA) |
|
Tyrosine 2,3-aminomutase activity GO:0050368
Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.
|
3 | Q1LRV9 (/IDA) Q1LRV9 (/IDA) Q8GMG0 (/IDA) |
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
2 | P35492 (/ISO) P35492 (/ISO) |
|
Ammonia-lyase activity GO:0016841
Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
|
2 | Q1LRV9 (/IDA) Q1LRV9 (/IDA) |
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
1 | P42357 (/EXP) |
|
Histidine ammonia-lyase activity GO:0004397
Catalysis of the reaction: L-histidine = urocanate + NH3.
|
1 | P21213 (/TAS) |
|
Tyrosine ammonia-lyase activity GO:0052883
Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate.
|
1 | Q8GMG0 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
|
7 | Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) Q9KSQ4 (/ISS) |
|
Histidine catabolic process GO:0006548
The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
|
7 | Q20502 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) Q9HU85 (/IMP) |
|
Histidine catabolic process GO:0006548
The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
|
2 | P35492 (/IDA) P35492 (/IDA) |
|
Histidine metabolic process GO:0006547
The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
|
1 | P21213 (/TAS) |
|
Histidine catabolic process GO:0006548
The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
|
1 | P42357 (/TAS) |
|
Toxin biosynthetic process GO:0009403
The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | Q8GMG0 (/IDA) |
|
Zinc ion homeostasis GO:0055069
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
1 | Q20502 (/IMP) |
|
Hematopoietic stem cell differentiation GO:0060218
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
1 | A4FUP1 (/IMP) |
|
Stress response to zinc ion GO:1990359
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.
|
1 | Q20502 (/IGI) |
|
Stress response to zinc ion GO:1990359
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.
|
1 | Q20502 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P21213 (/TAS) P42357 (/TAS) |
