CATH Superfamily 1.10.840.10
Ras guanine-nucleotide exchange factors catalytic domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ras guanine-nucleotide exchange factors catalytic domain
".
FunFam 10: ras-specific guanine nucleotide-releasing factor R...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
8 | Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) |
|
Ral guanyl-nucleotide exchange factor activity GO:0008321
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
8 | Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) |
|
Ral guanyl-nucleotide exchange factor activity GO:0008321
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
2 | Q0E949 (/ISS) Q8MT78 (/ISS) |
|
Ral guanyl-nucleotide exchange factor activity GO:0008321
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
1 | A2AR50 (/ISO) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of Ral protein signal transduction GO:0032485
Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
|
8 | Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) Q5JS13 (/IDA) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
8 | Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) Q5JS13 (/NAS) |
|
Regulation of Ral protein signal transduction GO:0032485
Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
|
2 | Q0E949 (/ISS) Q8MT78 (/ISS) |
|
Regulation of Ral protein signal transduction GO:0032485
Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
|
1 | A2AR50 (/ISO) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
