The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ras guanine-nucleotide exchange factors catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
GEF
575 - - 72.3
2
487
3D
4mh0E05 - 85.7
6
396
3D
6eppS02 - 68.5
3
392
3D
4l9mA02 - 89.2
4
349
3D
2ijeS00 - 67.0
5
347 - - 72.7
7
Predicted
328
3D
3t6gC00 - 83.6
8
286 - - 72.2
9
206 - - 90.8
10
191
3D
3qxlB00 - 55.7
11
124 - - 62.0
12
79
3D
4jgwB02 - 45.2
13
77 - - 77.9
14
38 - - 58.3
15
36 - - 90.4
16
32 - - 68.8
17
22 - - 20.4
18
17 - - 6.3
20
13 - - 6.0
19
13 - - 73.9
22
10 - - 10.4
21
10 - - 8.5
23
10 - - 34.9
24
8 - - 16.0
26
6 - - 0.0
25
6 - - 13.6
29
3 - - 63.0
30
3 - - 1.5
31
3 - - 3.3
27
3 - - 7.7
28
3 - - 9.0
37
2 - - 0.0
33
2 - - 36.2
32
2 - - 29.2
34
2 - - 1.7
36
2 - - 0.0
38
2 - - 39.6
35
2 - - 0.0
39
1 - - 0.0
48
1 - - 0.0
41
1 - - 0.0
43
1 - - 0.0
51
1 - - 0.0
46
1 - - 0.0
40
1 - - 0.0
44
1 - - 0.0
49
1 - - 0.0
42
1 - - 0.0
50
1 - - 0.0
45
1 - - 0.0
47
1 - - 0.0
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