The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: cytochrome P450 4F22 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 48 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arachidonic acid epoxygenase activity GO:0008392
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Alkane 1-monooxygenase activity GO:0018685
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Leukotriene-B4 20-monooxygenase activity GO:0050051
Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
6 A2A974 (/ISO) B0G0Y1 (/ISO) B0G0Y2 (/ISO) Q64462 (/ISO) Q64462 (/ISO) Q91WL5 (/ISO)
Arachidonic acid monooxygenase activity GO:0008391
Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
6 A2A8T1 (/ISO) F8WGU9 (/ISO) O35728 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q9EP75 (/ISO)
Alkane 1-monooxygenase activity GO:0018685
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
6 A2A8T1 (/ISO) F8WGU9 (/ISO) O35728 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q99N16 (/ISO)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
5 O88833 (/TAS) P15129 (/TAS) Q08477 (/TAS) Q08477 (/TAS) Q6NT55 (/TAS)
Arachidonic acid epoxygenase activity GO:0008392
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
5 A2A8T1 (/ISO) F8WGU9 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q99N16 (/ISO)
Leukotriene-B4 20-monooxygenase activity GO:0050051
Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O.
5 A2A8T1 (/ISO) F8WGU9 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q99N16 (/ISO)
Laurate hydroxylase activity GO:0102116
Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O
4 A2A974 (/ISO) B0G0Y1 (/ISO) B0G0Y2 (/ISO) Q91WL5 (/ISO)
16-hydroxypalmitate dehydrogenase activity GO:0103002
Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH
4 A2A974 (/ISO) B0G0Y1 (/ISO) B0G0Y2 (/ISO) Q91WL5 (/ISO)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
3 B2RY43 (/ISO) G3UW81 (/ISO) O35728 (/ISO)
Arachidonic acid monooxygenase activity GO:0008391
Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
3 P08516 (/IMP) P20816 (/IMP) P20817 (/IMP)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
3 B2RY43 (/ISO) G3UW81 (/ISO) Q99N16 (/ISO)
Alkane 1-monooxygenase activity GO:0018685
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
3 P78329 (/IDA) Q02928 (/IDA) Q91WL5 (/IDA)
Alkane 1-monooxygenase activity GO:0018685
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
3 P08516 (/IMP) P20816 (/IMP) P20817 (/IMP)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
3 Q8VCA4 (/ISO) Q99N18 (/ISO) Q9EP75 (/ISO)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
2 P15129 (/IDA) P24464 (/IDA)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 P20816 (/IDA) Q9HBI6 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 Q64462 (/ISO) Q64462 (/ISO)
Arachidonic acid monooxygenase activity GO:0008391
Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
2 P08516 (/IDA) P33274 (/IDA)
Arachidonic acid epoxygenase activity GO:0008392
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
2 P78329 (/IDA) Q02928 (/IDA)
Toxic substance binding GO:0015643
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
2 Q64462 (/ISO) Q64462 (/ISO)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2 P78329 (/IDA) Q9HBI6 (/IDA)
Fluorene oxygenase activity GO:0018585
Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.
2 Q64462 (/ISO) Q64462 (/ISO)
Alkane 1-monooxygenase activity GO:0018685
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
2 P98187 (/TAS) Q02928 (/TAS)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 P33274 (/IDA) P51869 (/IDA)
Leukotriene-B4 20-monooxygenase activity GO:0050051
Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O.
2 P78329 (/IDA) Q02928 (/IDA)
Arachidonic acid binding GO:0050544
Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2 P20816 (/IDA) P33274 (/IDA)
Arachidonic acid binding GO:0050544
Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2 O35728 (/ISO) Q9EP75 (/ISO)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
1 P15129 (/IMP)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
1 Q91WL5 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P78329 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P15129 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P15129 (/IMP)
Arachidonic acid 11,12-epoxygenase activity GO:0008405
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.
1 P20816 (/TAS)
Toxic substance binding GO:0015643
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
1 P15129 (/IDA)
Fluorene oxygenase activity GO:0018585
Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.
1 P15129 (/IDA)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
1 P13584 (/TAS)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
1 Q9HBI6 (/TAS)
Arachidonic acid omega-hydroxylase activity GO:0052869
Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.
1 P78329 (/IDA)
Arachidonic acid omega-hydroxylase activity GO:0052869
Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.
1 Q99N16 (/ISO)
Alpha-tocopherol omega-hydroxylase activity GO:0052871
Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O .
1 P78329 (/IDA)
Alpha-tocopherol omega-hydroxylase activity GO:0052871
Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O .
1 Q99N16 (/ISO)
Tocotrienol omega-hydroxylase activity GO:0052872
Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O .
1 P78329 (/IDA)
Tocotrienol omega-hydroxylase activity GO:0052872
Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O .
1 Q99N16 (/ISO)
Laurate hydroxylase activity GO:0102116
Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O
1 Q5TCH4 (/IDA)
16-hydroxypalmitate dehydrogenase activity GO:0103002
Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH
1 Q5TCH4 (/IDA)

There are 81 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Very long-chain fatty acid metabolic process GO:0000038
The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Long-chain fatty acid metabolic process GO:0001676
The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Renal water homeostasis GO:0003091
Renal process involved in the maintenance of an internal steady state of water in the body.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Pressure natriuresis GO:0003095
The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Epoxygenase P450 pathway GO:0019373
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Leukotriene B4 catabolic process GO:0036101
The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Vitamin E metabolic process GO:0042360
The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Icosanoid metabolic process GO:0006690
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
5 P78329 (/TAS) P98187 (/TAS) Q08477 (/TAS) Q08477 (/TAS) Q6NT55 (/TAS)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
4 P08516 (/IEP) P20816 (/IEP) P20817 (/IEP) P24464 (/IEP)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
4 P24464 (/IDA) P33274 (/IDA) P78329 (/IDA) Q02928 (/IDA)
Lauric acid metabolic process GO:0048252
The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
4 P08516 (/IDA) P20816 (/IDA) P20817 (/IDA) P24464 (/IDA)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
3 P78329 (/TAS) Q08477 (/TAS) Q08477 (/TAS)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
3 P51870 (/TAS) P51871 (/TAS) Q9HBI6 (/TAS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
3 P08516 (/IMP) P20816 (/IMP) P20817 (/IMP)
Menaquinone catabolic process GO:0042361
The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
3 B2RY43 (/ISO) G3UW81 (/ISO) Q99N16 (/ISO)
Phylloquinone catabolic process GO:0042376
The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
3 B2RY43 (/ISO) G3UW81 (/ISO) Q99N16 (/ISO)
Vitamin K catabolic process GO:0042377
The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
3 B2RY43 (/ISO) G3UW81 (/ISO) Q99N16 (/ISO)
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
3 P08516 (/IDA) P20816 (/IDA) P20817 (/IDA)
Icosanoid biosynthetic process GO:0046456
The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
3 P08516 (/IMP) P20816 (/IMP) P20817 (/IMP)
Long-chain fatty acid metabolic process GO:0001676
The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
2 P78329 (/IDA) Q02928 (/IDA)
Renal water homeostasis GO:0003091
Renal process involved in the maintenance of an internal steady state of water in the body.
2 P78329 (/IEP) Q02928 (/IEP)
Pressure natriuresis GO:0003095
The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).
2 P78329 (/IEP) Q02928 (/IEP)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 P24464 (/IDA) Q9HBI6 (/IDA)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 B2RY43 (/ISO) G3UW81 (/ISO)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 O88833 (/TAS) Q02928 (/TAS)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2 P51870 (/IMP) P51871 (/IMP)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
2 Q99KY6 (/ISO) Q99N19 (/ISO)
Cellular aromatic compound metabolic process GO:0006725
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
2 Q64462 (/ISO) Q64462 (/ISO)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
2 P78329 (/TAS) Q9HBI6 (/TAS)
Biphenyl metabolic process GO:0018879
The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
2 Q64462 (/ISO) Q64462 (/ISO)
Fluorene metabolic process GO:0018917
The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2 Q64462 (/ISO) Q64462 (/ISO)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2 Q99N16 (/ISO) Q9EP75 (/ISO)
Epoxygenase P450 pathway GO:0019373
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
2 P78329 (/IDA) Q02928 (/IDA)
Positive regulation of icosanoid secretion GO:0032305
Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.
2 P78329 (/IMP) Q02928 (/IMP)
Menaquinone catabolic process GO:0042361
The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
2 P78329 (/IDA) Q9HBI6 (/IDA)
Phylloquinone catabolic process GO:0042376
The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
2 P78329 (/IDA) Q9HBI6 (/IDA)
Vitamin K catabolic process GO:0042377
The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
2 P78329 (/IDA) Q9HBI6 (/IDA)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
2 Q64462 (/ISO) Q64462 (/ISO)
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
2 P78329 (/IEP) Q02928 (/IEP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 P78329 (/IDA) Q02928 (/IDA)
Omega-hydroxylase P450 pathway GO:0097267
The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
2 P78329 (/TAS) Q02928 (/TAS)
Very long-chain fatty acid metabolic process GO:0000038
The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
1 P78329 (/IDA)
Very long-chain fatty acid metabolic process GO:0000038
The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
1 Q99N16 (/ISO)
Long-chain fatty acid metabolic process GO:0001676
The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
1 Q99N16 (/ISO)
Placenta development GO:0001890
The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1 P08516 (/IEP)
Lipid hydroxylation GO:0002933
The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
1 Q5TCH4 (/IDA)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
1 Q91WL5 (/ISS)
Icosanoid metabolic process GO:0006690
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
1 P33274 (/IDA)
Icosanoid metabolic process GO:0006690
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
1 Q9EP75 (/ISO)
Leukotriene metabolic process GO:0006691
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
1 Q02928 (/IDA)
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
1 P98187 (/TAS)
Cellular aromatic compound metabolic process GO:0006725
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
1 P15129 (/IDA)
Cellular aromatic compound metabolic process GO:0006725
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
1 P15129 (/IMP)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
1 P78329 (/IMP)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
1 Q99N16 (/ISO)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 P33274 (/IEP)
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
1 P20816 (/IEP)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
1 P78329 (/IMP)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
1 Q99N16 (/ISO)
Biphenyl metabolic process GO:0018879
The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
1 P15129 (/IMP)
Fluorene metabolic process GO:0018917
The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
1 P15129 (/IDA)
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
1 Q02928 (/TAS)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
1 P20816 (/TAS)
Epoxygenase P450 pathway GO:0019373
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
1 Q99N16 (/ISO)
Negative regulation of icosanoid secretion GO:0032304
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.
1 P78329 (/IMP)
Negative regulation of icosanoid secretion GO:0032304
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.
1 Q99N16 (/ISO)
Positive regulation of icosanoid secretion GO:0032305
Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.
1 Q99N16 (/ISO)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 P24464 (/IEP)
Leukotriene B4 catabolic process GO:0036101
The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
1 P78329 (/IDA)
Leukotriene B4 catabolic process GO:0036101
The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
1 Q99N16 (/ISO)
Vitamin E metabolic process GO:0042360
The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
1 P78329 (/IDA)
Vitamin E metabolic process GO:0042360
The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
1 Q99N16 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P20816 (/IEP)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
1 P15129 (/IDA)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
1 P15129 (/IMP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 Q99N16 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 Q9HBI6 (/TAS)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
13 A2A8T1 (/ISO) A2A974 (/ISO) B0G0Y1 (/ISO) B0G0Y2 (/ISO) F8WGU9 (/ISO) O35728 (/ISO) O88833 (/ISO) Q64462 (/ISO) Q64462 (/ISO) Q91WL5 (/ISO)
(3 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
10 P13584 (/TAS) P78329 (/TAS) P98187 (/TAS) Q02928 (/TAS) Q08477 (/TAS) Q08477 (/TAS) Q6NT55 (/TAS) Q9HBI6 (/TAS) Q9HCS2 (/TAS) Q9HCS2 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
9 O88833 (/IDA) P08516 (/IDA) P15129 (/IDA) P20816 (/IDA) P20817 (/IDA) P24464 (/IDA) P33274 (/IDA) P78329 (/IDA) Q02928 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
9 A8CBR4 (/ISS) F6QKZ2 (/ISS) F7GYF6 (/ISS) G1R002 (/ISS) G1R020 (/ISS) G3RZG3 (/ISS) Q5RDY6 (/ISS) Q9HCS2 (/ISS) Q9HCS2 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 A2A8T1 (/ISO) F8WGU9 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q99N16 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
5 A2A8T1 (/ISO) F8WGU9 (/ISO) O88833 (/ISO) Q91WU1 (/ISO) Q99N16 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 A2A974 (/ISO) B0G0Y1 (/ISO) B0G0Y2 (/ISO) Q91WL5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P78329 (/IDA) Q02928 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 P78329 (/IDA) Q02928 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q5TCH4 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P24464 (/TAS)