The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Calponin-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Parvin, beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
20 Q9EPC1 (/IPI) Q9ES46 (/IPI) Q9ES46 (/IPI) Q9HBI0 (/IPI) Q9HBI0 (/IPI) Q9HBI1 (/IPI) Q9NVD7 (/IPI) Q9NVD7 (/IPI) Q9NVD7 (/IPI) Q9NVD7 (/IPI)
(10 more)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
14 Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA)
(4 more)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q9HBI0 (/TAS) Q9HBI0 (/TAS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 Q9EPC1 (/IDA)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q9HB97 (/IC)

There are 41 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Heterotypic cell-cell adhesion GO:0034113
The attachment of a cell to a cell of a different type via adhesion molecules.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
15 Q9EPC1 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP)
(5 more)
Actin-mediated cell contraction GO:0070252
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Smooth muscle cell chemotaxis GO:0071670
The directed movement of a smooth muscle cell in response to an external stimulus.
15 Q9HB97 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS) Q9NVD7 (/ISS)
(5 more)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
14 Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP) Q9NVD7 (/IMP)
(4 more)
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
4 Q09SN9 (/IMP) Q6PC42 (/IMP) X1WCE0 (/IMP) X1WFZ4 (/IMP)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
4 Q09SN9 (/IMP) Q6PC42 (/IMP) X1WCE0 (/IMP) X1WFZ4 (/IMP)
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
2 Q9HBI0 (/TAS) Q9HBI0 (/TAS)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
2 Q9ES46 (/ISO) Q9ES46 (/ISO)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
2 Q9ES46 (/ISS) Q9ES46 (/ISS)
Lamellipodium assembly GO:0030032
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
2 Q9ES46 (/ISO) Q9ES46 (/ISO)
Lamellipodium assembly GO:0030032
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
2 Q9ES46 (/ISS) Q9ES46 (/ISS)
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
2 Q9ES46 (/ISO) Q9ES46 (/ISO)
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
2 Q9ES46 (/ISS) Q9ES46 (/ISS)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
2 Q9EPC1 (/ISS) Q9HB97 (/ISS)
Establishment or maintenance of cell polarity regulating cell shape GO:0071963
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
2 Q9ES46 (/ISO) Q9ES46 (/ISO)
Establishment or maintenance of cell polarity regulating cell shape GO:0071963
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
2 Q9ES46 (/ISS) Q9ES46 (/ISS)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
1 Q9EPC1 (/IMP)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
1 Q9EPC1 (/IMP)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q9EPC1 (/IDA)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
1 Q9EPC1 (/IMP)
Apposition of dorsal and ventral imaginal disc-derived wing surfaces GO:0007475
The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
1 Q9VWD0 (/IMP)
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
1 Q9VWD0 (/IMP)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
1 Q9HBI1 (/IMP)
Lamellipodium assembly GO:0030032
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
1 Q9HBI1 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q9HB97 (/IDA)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q9EPC1 (/ISO)
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q9HBI1 (/IMP)
Heterotypic cell-cell adhesion GO:0034113
The attachment of a cell to a cell of a different type via adhesion molecules.
1 Q9EPC1 (/IMP)
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
1 Q9EPC1 (/ISO)
Substrate adhesion-dependent cell spreading GO:0034446
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
1 Q9HB97 (/ISS)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9HB97 (/IDA)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9HB97 (/IPI)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9EPC1 (/ISO)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q9EPC1 (/ISO)
Actin-mediated cell contraction GO:0070252
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
1 Q9EPC1 (/IMP)
Smooth muscle cell chemotaxis GO:0071670
The directed movement of a smooth muscle cell in response to an external stimulus.
1 Q9EPC1 (/IMP)
Establishment or maintenance of cell polarity regulating cell shape GO:0071963
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
1 Q9HBI1 (/IMP)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
22 E9PS97 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) Q9EPC1 (/IDA) Q9HBI1 (/IDA) Q9NVD7 (/IDA) Q9NVD7 (/IDA) Q9NVD7 (/IDA)
(12 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 Q9HBI1 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS) Q9NVD7 (/TAS)
(5 more)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
14 Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA) Q9NVD7 (/HDA)
(4 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 E9PS97 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
5 E9PS97 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA) J3KNQ4 (/IDA)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
4 Q09SN9 (/IDA) Q6PC42 (/IDA) X1WCE0 (/IDA) X1WFZ4 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
3 Q9EPC1 (/ISO) Q9ES46 (/ISO) Q9ES46 (/ISO)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
3 Q9ES46 (/ISS) Q9ES46 (/ISS) Q9HB97 (/ISS)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
2 Q9HBI0 (/TAS) Q9HBI0 (/TAS)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
2 Q9EPC1 (/IDA) Q9HBI1 (/IDA)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
2 Q9ES46 (/ISO) Q9ES46 (/ISO)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
2 Q9ES46 (/ISS) Q9ES46 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9EPC1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9EPC1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9EPC1 (/ISO)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q9HB97 (/NAS)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 Q9EPC1 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9HB97 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9EPC1 (/ISO)
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