The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 65: calpain-3 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 33 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Sodium ion binding GO:0031402
Interacting selectively and non-covalently with sodium ions (Na+).
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Ligase regulator activity GO:0055103
Modulates the activity of a ligase.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Titin binding GO:0031432
Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Calcium-dependent cysteine-type endopeptidase activity GO:0004198
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
8 P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Calcium-dependent cysteine-type endopeptidase activity GO:0004198
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
3 P16259 (/TAS) P20807 (/TAS) Q9UMQ6 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P16259 (/IPI) P20807 (/IPI) Q64691 (/IPI)
Calcium-dependent cysteine-type endopeptidase activity GO:0004198
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
2 P16259 (/IDA) Q64691 (/IDA)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
2 P16259 (/IDA) P20807 (/IDA)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
1 P20807 (/IDA)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
1 Q64691 (/ISO)
Calcium-dependent cysteine-type endopeptidase activity GO:0004198
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
1 Q64691 (/ISO)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P16259 (/IPI)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q64691 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q64691 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P16259 (/TAS)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
1 Q64691 (/ISO)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
1 Q9UMQ6 (/TAS)
Cysteine-type peptidase activity GO:0008234
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
1 P20807 (/TAS)
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
1 Q64691 (/IMP)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P16259 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q64691 (/ISO)
Sodium ion binding GO:0031402
Interacting selectively and non-covalently with sodium ions (Na+).
1 Q64691 (/IDA)
Titin binding GO:0031432
Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
1 P16259 (/IDA)
Titin binding GO:0031432
Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
1 P20807 (/IPI)
Titin binding GO:0031432
Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
1 Q64691 (/ISO)
Ligase regulator activity GO:0055103
Modulates the activity of a ligase.
1 P20807 (/IDA)
Ligase regulator activity GO:0055103
Modulates the activity of a ligase.
1 Q64691 (/ISO)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
1 Q64691 (/IMP)

There are 71 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718
Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Negative regulation of protein sumoylation GO:0033234
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Positive regulation of proteolysis GO:0045862
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122
Any process that modulates I-kappaB kinase/NF-kappaB signaling.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
18 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(8 more)
Calcium-dependent self proteolysis GO:1990092
The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
10 E9QE31 (/ISS) P16259 (/ISS) P43368 (/ISS) P51186 (/ISS) Q64691 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Positive regulation of release of sequestered calcium ion into cytosol GO:0051281
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
9 P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q64691 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Muscle structure development GO:0061061
The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Protein localization to membrane GO:0072657
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
9 P16259 (/ISS) P20807 (/ISS) P43368 (/ISS) P51186 (/ISS) Q92177 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9GLG7 (/ISS) Q9TTH8 (/ISS)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
3 P16259 (/IDA) P20807 (/IDA) Q64691 (/IDA)
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
3 A0A2R8Q1U8 (/IGI) E9QE31 (/IGI) F1R632 (/IGI)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P20807 (/IMP) Q64691 (/IMP)
Regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122
Any process that modulates I-kappaB kinase/NF-kappaB signaling.
2 P20807 (/IMP) Q64691 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 P20807 (/IMP) Q64691 (/IMP)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
2 P20807 (/IMP) Q64691 (/IMP)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
2 P16259 (/IDA) P20807 (/IDA)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 Q64691 (/ISO)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 P16259 (/TAS)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P20807 (/TAS)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
1 P20807 (/TAS)
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
1 Q64691 (/IDA)
Positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718
Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
1 Q64691 (/IDA)
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
1 P16259 (/IDA)
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
1 Q64691 (/ISO)
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
1 P20807 (/IMP)
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
1 Q64691 (/ISO)
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
1 Q64691 (/IMP)
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
1 P20807 (/TAS)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
1 P20807 (/IMP)
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
1 Q64691 (/ISO)
Negative regulation of protein sumoylation GO:0033234
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
1 P20807 (/IDA)
Negative regulation of protein sumoylation GO:0033234
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
1 Q64691 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P16259 (/IEP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q64691 (/ISO)
Regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122
Any process that modulates I-kappaB kinase/NF-kappaB signaling.
1 Q64691 (/ISO)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 Q64691 (/IMP)
Regulation of myoblast differentiation GO:0045661
Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
1 Q64691 (/IDA)
Positive regulation of proteolysis GO:0045862
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
1 Q64691 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q64691 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q64691 (/ISO)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
1 P20807 (/TAS)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
1 P20807 (/IDA)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
1 Q64691 (/ISO)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
1 Q64691 (/ISO)
Positive regulation of release of sequestered calcium ion into cytosol GO:0051281
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
1 Q64691 (/IMP)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 P16259 (/IDA)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q64691 (/ISO)
Muscle structure development GO:0061061
The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
1 Q64691 (/IMP)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q64691 (/IMP)
G1 to G0 transition involved in cell differentiation GO:0070315
A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.
1 Q64691 (/IDA)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q64691 (/IDA)
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q64691 (/IDA)
Protein localization to membrane GO:0072657
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
1 Q64691 (/IMP)
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 Q64691 (/ISO)
Sodium-dependent self proteolysis GO:1990091
The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 P16259 (/IDA)
Sodium-dependent self proteolysis GO:1990091
The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 Q64691 (/ISO)
Calcium-dependent self proteolysis GO:1990092
The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 P20807 (/IDA)
Calcium-dependent self proteolysis GO:1990092
The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1 Q64691 (/ISO)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Myofibril GO:0030016
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
20 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(10 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
19 B5AFM5 (/ISS) E2R8T7 (/ISS) G1KRC7 (/ISS) G1MBZ6 (/ISS) G1QWI5 (/ISS) G1TSG0 (/ISS) G3TVX4 (/ISS) G3VZS1 (/ISS) G5BM28 (/ISS) G7MWY9 (/ISS)
(9 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P16259 (/IDA) P20807 (/IDA) Q64691 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P16259 (/IDA) P20807 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P16259 (/IDA) Q64691 (/IDA)
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
1 Q6J756 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 P20807 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q64691 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q64691 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q64691 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q64691 (/ISO)
Myofibril GO:0030016
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
1 P16259 (/IDA)
Myofibril GO:0030016
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
1 Q64691 (/ISO)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 P16259 (/IDA)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 Q64691 (/ISO)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 P16259 (/IDA)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 Q64691 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q64691 (/IDA)