The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histone, subunit A
".
FunFam 223:
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9V6Q2 (/IPI) Q9V6Q2 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
2 | Q9V6Q2 (/IMP) Q9V6Q2 (/IMP) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
2 | Q9V6Q2 (/IMP) Q9V6Q2 (/IMP) |
|
Mitotic metaphase plate congression GO:0007080
The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.
|
2 | Q9V6Q2 (/IMP) Q9V6Q2 (/IMP) |
|
Positive regulation of chromatin silencing GO:0031937
Any process that activates or increases the frequency, rate or extent of chromatin silencing.
|
2 | Q9V6Q2 (/IGI) Q9V6Q2 (/IGI) |
|
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
|
2 | Q9V6Q2 (/IMP) Q9V6Q2 (/IMP) |
|
Kinetochore assembly GO:0051382
The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q9V6Q2 (/IMP) Q9V6Q2 (/IMP) |
|
Kinetochore organization GO:0051383
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome, centromeric region GO:0000775
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
|
Condensed nuclear chromosome, centromeric region GO:0000780
The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
|
Nuclear nucleosome GO:0000788
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures.
|
2 | Q9V6Q2 (/IPI) Q9V6Q2 (/IPI) |
|
Condensed nuclear chromosome inner kinetochore GO:0000941
The region of a condensed nuclear chromosome kinetochore closest to centromeric DNA; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome.
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |
|
CENP-A containing nucleosome GO:0043505
A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
|
2 | Q9V6Q2 (/IDA) Q9V6Q2 (/IDA) |