The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Transcription Factor, Ets-1
".
FunFam 59: E3 ubiquitin-protein ligase LRSAM1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q6UWE0 (/IPI) Q6UWE0 (/IPI) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q80ZI6 (/ISO) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
1 | Q80ZI6 (/ISO) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
1 | Q80ZI6 (/ISS) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q6UWE0 (/IMP) Q6UWE0 (/IMP) |
|
Negative regulation of endocytosis GO:0045806
Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
|
2 | Q6UWE0 (/IMP) Q6UWE0 (/IMP) |
|
Negative regulation of endocytosis GO:0045806
Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Viral budding GO:0046755
A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
|
2 | Q6UWE0 (/IMP) Q6UWE0 (/IMP) |
|
Viral budding GO:0046755
A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Ubiquitin-dependent endocytosis GO:0070086
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Ubiquitin-dependent endocytosis GO:0070086
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Positive regulation of xenophagy GO:1904417
Any process that activates or increases the frequency, rate or extent of xenophagy.
|
2 | Q6UWE0 (/IMP) Q6UWE0 (/IMP) |
|
Positive regulation of autophagosome assembly GO:2000786
Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
|
2 | Q6UWE0 (/IMP) Q6UWE0 (/IMP) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
1 | Q80ZI6 (/ISO) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
1 | Q80ZI6 (/ISS) |
|
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q80ZI6 (/ISO) |
|
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q80ZI6 (/ISS) |
|
Negative regulation of endocytosis GO:0045806
Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
|
1 | Q80ZI6 (/ISO) |
|
Viral budding GO:0046755
A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
|
1 | Q80ZI6 (/ISO) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
1 | Q80ZI6 (/ISO) |
|
Ubiquitin-dependent endocytosis GO:0070086
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
|
1 | Q80ZI6 (/ISO) |
|
Positive regulation of xenophagy GO:1904417
Any process that activates or increases the frequency, rate or extent of xenophagy.
|
1 | Q80ZI6 (/ISO) |
|
Positive regulation of xenophagy GO:1904417
Any process that activates or increases the frequency, rate or extent of xenophagy.
|
1 | Q80ZI6 (/ISS) |
|
Positive regulation of autophagosome assembly GO:2000786
Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
|
1 | Q80ZI6 (/ISO) |
|
Positive regulation of autophagosome assembly GO:2000786
Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
|
1 | Q80ZI6 (/ISS) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0A024R870 (/IDA) A0A024R870 (/IDA) Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q6UWE0 (/IDA) Q6UWE0 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q08E63 (/ISS) Q80ZI6 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q80ZI6 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q80ZI6 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q80ZI6 (/ISO) |
