CATH Superfamily 1.10.150.50

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Ephrin type-A receptor 5	1406	3D	1b0xA00	-	91.1
2	PTPRF interacting protein alpha 1	1355	3D	3tadB02	-	76.0
3	liprin-alpha-2 isoform X1	967	3D	3tadB01	-	67.7
4	PTPRF interacting protein alpha 1	929	3D	3tadB03	-	91.0
5	Liprin-beta-1 isoform 1	878	3D	3tadD02	-	77.1
6	SH3 and multiple ankyrin repeat domains protein 2	638	3D	2f44C00	-	90.6
7	Liprin-beta-1 isoform 1	612	3D	3tadD03	-	86.5
8	Neurabin-1 isoform 1-like protein	593	3D	2gleA00	-	97.0
9	Stromal interaction molecule 1	571	3D	2k60A02	-	92.9
10	Fli-1 proto-oncogene, ETS transcription factor	569	3D	1sxeA00	-	86.4
12	Poly [ADP-ribose] polymerase	531	3D	5kniG00	-	90.9
11	Polyhomeotic-like protein 2 isoform 1	530	3D	4pzoF00	-	75.6
13	Protein Smaug homolog 1 isoform 2	474		-	-	73.4
14	Protein c-ets-1 isoform 1	473	3D	2kmdA01	-	93.3
16	Ankyrin repeat and sterile alpha motif domain-containing protein 1B	469	3D	2kivA01	-	68.7
15	ankyrin repeat and sterile alpha motif domain-containing protein 1B	468	3D	2kivA02	-	58.4
17	Liprin-beta-1 isoform 1	438		-	-	76.8
18	Polycomb protein scmh1 isoform 4	424		-	-	78.7
19	Connector enhancer of kinase suppressor of Ras 2	407	3D	3bs5B00	-	81.6
20	Tumor protein 63 p63	373	3D	5n2oA00	-	80.4
21	Diacylglycerol kinase	350	3D	3bq7F00	-	79.3
22	Transcription factor CP2 like 1	334		-	-	70.4
23	Epidermal growth factor receptor kinase substrate 8	323	3D	2e8mA01	-	95.5
25	Ankyrin repeat and sterile alpha motif domain-containing 6	322	3D	4rqnC01	-	80.6
24	Putative sam and sh3 domain-containing protein 1	321		-	-	76.3
26	ETS homologous factor isoform X1	292		-	-	82.5
30	transcription factor ETV6	266	3D	2qb1B00	-	83.8
27	scm-like with four MBT domains protein 2	261		-	-	47.0
29	Ephrin type-A receptor 1	259	3D	3kkaE00	-	89.7
28	caskin-2 isoform X2	259	3D	3senD01	-	89.6
32	caskin-1 isoform X1	224	3D	3senD02	-	81.4
33	Protein vts1, variant	218	3D	2fe9A00	-	85.8
31	Kinase suppressor of Ras 2	218	3D	2lpeA02	-	94.7
34	ankyrin repeat and SAM domain-containing protein 4B	199	3D	5f3xD00	-	97.0
35	lethal 3	188		-	-	58.0
37	sphingomyelin synthase-related protein 1 isoform X1	178		-	-	87.9
36	upstream-binding protein 1 isoform X1	178		-	-	81.8
38	Putative sam and sh3 domain-containing protein 1	176	3D	2dl0A01	-	80.3
39	GA-binding protein alpha chain, putative	162	3D	1sxdA00	-	92.1
40	Phosphatidylcholine:ceramide cholinephosphotransferase 1	157	3D	2d8cA01	-	80.8
41	Chromosome 19 C19orf47 homolog	154		-	-	66.1
42	GRB2-associated and regulator of MAPK protein 1	153	3D	2dkzA01	-	50.4
43	Sterile alpha and TIR motif-containing 1	149		-	-	86.0
44	kinase D-interacting substrate of 220 kDa isoform X1	136		-	-	74.4
45	SAM domain, SH3 domain and nuclear localization signals 1	130	3D	1v38A00	-	72.1
46	ephrin type-A receptor 3	123		-	-	81.6
49	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	122	3D	2ksoB00	-	52.2
50	SAM pointed domain containing ETS transcription factor	121	3D	2dkxA00	-	87.2
47	SEC23 interacting protein	121		-	-	71.7
48	kazrin isoform X1	120		-	-	60.0
51	Lymphocyte cytosolic protein 2	119	3D	2eapA01	-	90.2
52	Kinesin family member 24	105		-	-	78.0
53	Bifunctional apoptosis regulator	103	3D	1v85A00	-	83.2
54	Sterile alpha motif domain-containing protein	101		-	-	73.0
55	Sterile alpha motif domain containing 5	96	3D	5zrzB00	-	95.4
56	Ectoderm-expressed 4, isoform D	94		-	-	84.8
57	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3	93	3D	2kg5A01	-	75.1
58	ephrin type-A receptor 8	92	3D	1ucvA00	-	75.1
61	Ets DNA-binding protein pokkuri	92	3D	1sv4B00	-	91.3
59	E3 ubiquitin-protein ligase LRSAM1 isoform X1	88		-	-	74.3
60	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1	86		-	-	81.0
63	ETS-related transcription factor Elf-3 isoform X1	85	3D	2e8pA01	-	77.1
62	Sterile alpha and TIR motif containing 1	84		-	-	81.3
64	arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1	74		-	-	56.6
65	mitogen-activated protein kinase kinase kinase 20 isoform X1	68		-	-	80.5
66	ephrin type-A receptor 10	62		-	-	77.4
67	SAM and HD domain-containing deoxynucleoside triphosphate triphosphohydrolase 1	58	3D	2e8oA01	-	94.4
68	Ephrin type-B receptor 6	56		-	-	58.2
69	mitochondrial import inner membrane translocase subunit TIM22-like	55		-	-	65.0
70	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	47		-	-	40.1
71	Caskin, isoform D	43		-	-	95.4
72	Sexual stage-specific protein kinase	41		-	-	23.2
73	Gemini, isoform C	41		-	-	72.9
74	Stromal interaction molecule	40		-	-	93.3
75	Serine/threonine-protein kinase STE11	37		-	-	78.9
76	Smg, isoform B	36	3D	1oxjA01	-	57.6
77	DDHD domain-containing 2	35		-	-	87.7
78	Sterile alpha motif SAM	34		-	-	73.4
80	Eph receptor tyrosine kinase	31		-	-	21.8
79	transcription factor CP2-like protein 1 isoform X1	31		-	-	60.0
81	EPS8 like 3	30		-	-	66.1
82	Polarized growth protein boi2	26		-	-	87.0
83	Kinase suppressor of ras	26		-	-	75.7
84	EPS Human endocytosis	25		-	-	90.3
85	Liprin-beta	24		-	-	14.9
86	Alpha-globin transcription factor CP2	24		-	-	88.2
87	Sterile alpha motif domain containing 9	23		-	-	86.2
89	Ankyrin repeat, SAM and basic leucine zipper domain-containing 1	22		-	-	94.7
91	polycomb protein Sfmbt isoform X1	22	3D	5j8yD00	-	18.2
88	Uncharacterized protein, isoform A	22		-	-	54.8
90	Bem1 interacting protein	21		-	-	62.5
92	Liprin-beta	20		-	-	20.8
94	Actin cytoskeleton-regulatory complex protein SLA1	20	3D	3idwA00	-	73.4
93	Sterile alpha motif domain-containing 7	19		-	-	67.0
95	uncharacterized protein LOC108099255 isoform X1	18		-	-	7.6
99	EPH receptor B2	16		-	-	16.9
96	Sterile alpha motif domain containing 9 like	16		-	-	61.9
98	Liprin-beta	16		-	-	0.0
97	Chromosome 19 C19orf47 homolog	16		-	-	2.6
100	Polycomb protein Scm	15		-	-	20.8
101	Sterile alpha and TIR motif-containing protein tir-1	15		-	-	64.8
105	Blast:Protein aveugle	14	3D	3bs7B00	-	18.2
103	Bicaudal C, isoform B	14		-	-	92.0
102	uncharacterized protein LOC108093779	14		-	-	23.6
104	Uncharacterized protein, isoform B	13		-	-	46.1
107	MAPKKK cascade protein kinase regulator Ste50 AFU_orthologue AFUA_2G17130	11		-	-	20.8
115	Serine/threonine-protein kinase STE11	11	3D	1x9xB00	-	0.0
108	Uncharacterized protein, isoform A	11		-	-	22.0
106	Diacylglycerol kinase	11		-	-	88.2
110	Mammalian ZAK kinase homolog	10		-	-	53.6
109	Ste50p	10		-	-	0.0
111	Predicted protein	10		-	-	83.6
112	Phospholipase DDHD2	9		-	-	8.5
113	DNA-binding protein D-ETS-6	9		-	-	86.5
116	Endonuclease III homolog	9		-	-	76.1
114	Kinesin-like protein	9		-	-	29.6
117	Kinase suppressor of Ras	8		-	-	6.8
118	Protein CBR-TAG-97	8		-	-	64.8
119	Kinesin-like protein	7		-	-	1.8
121	stromal interaction molecule 2	7		-	-	40.0
120	Adenylate cyclase, class 3	7		-	-	21.9
124	AGAP009560-PA-like protein	6		-	-	74.2
131	EPS8 like 2	6	3D	1wwuA01	-	45.0
126	Zmp:0000000735	6		-	-	96.0
123	Transcription factor ets-4	6		-	-	23.1
125	Protein CBG01454	6		-	-	15.0
122	CG5272 protein	6		-	-	11.9
129	Probable serine/threonine-protein kinase DDB_G0278535	5		-	-	86.6
133	Predicted protein	5		-	-	87.7
130	Serine/threonine-protein kinase, putative	5		-	-	16.1
128	Uncharacterized protein	5		-	-	62.3
132	Uncharacterized protein	5		-	-	83.0
134	ets protein isoform X1	5		-	-	77.3
127	Predicted protein	5		-	-	23.7
148	Probable serine/threonine-protein kinase samkC	4		-	-	77.8
141	Uncharacterized protein	4		-	-	72.0
143	Predicted protein	4		-	-	87.6
137	Sphingomyelin synthase-related 1	4		-	-	4.7
147	phosphatidylcholine:ceramide cholinephosphotransferase 2 isoform X1	4		-	-	77.3
135	Protein matrimony	4		-	-	9.2
145	GH09064p	4		-	-	15.9
140	Ephrin type-A receptor 5	4		-	-	14.2
142	Uncharacterized protein	4		-	-	85.2
149	uncharacterized protein LOC100179383 isoform X1	4		-	-	59.0
139	Uncharacterized protein	4		-	-	13.4
144	GD15078	4		-	-	11.3
136	Protein VTS1	4		-	-	13.0
146	Phosphatidylinositol 3-kinase regulatory subunit alpha-like Protein	4		-	-	85.7
138	E74-like factor 3 ets domain transcription factor, epithelial-specific	4		-	-	36.9
157	MAP kinase	3		-	-	0.0
163	Kinase suppressor of ras 1	3		-	-	64.9
154	Protein CBG04143	3		-	-	17.7
152	Ephrin type-A receptor 4-B	3		-	-	1.6
160	stromal interaction molecule homolog isoform X3	3		-	-	0.0
150	SAM_domain_ Sterile_alpha_motif	3		-	-	7.1
159	Putative adenylate cyclase	3		-	-	11.0
162	Serine/threonine-protein kinase STE11	3		-	-	0.0
158	Leucine-rich repeat and sterile alpha motif-containing 1	3		-	-	0.0
156	Uncharacterized protein, isoform A	3		-	-	4.7
153	Uncharacterized protein	3		-	-	39.0
155	STE11	3		-	-	0.0
161	Mitogen-activated protein kinase kinase kinase	3		-	-	0.0
164	Tyrosine kinase, non-receptor, 1	3		-	-	0.0
151	Putative ets proteinous factor	3		-	-	0.0
170	Uncharacterized protein	2		-	-	10.4
184	Uncharacterized protein	2		-	-	1.7
181	Uncharacterized protein	2		-	-	0.0
165	Uncharacterized protein	2		-	-	40.8
168	Uncharacterized protein	2		-	-	0.0
192	Putative sh3 and multiple ankyrin repeat 3	2		-	-	4.4
199	NGFI-A-binding protein 1a EGR1 binding protein 1	2		-	-	25.1
179	Predicted protein	2		-	-	49.5
193	Uncharacterized protein	2		-	-	0.0
186	Leucine-rich repeat and sterile alpha motif-containing 1	2		-	-	1.7
176	Protein tyrosine phosphatase, receptor type, f polypeptide PTPRF liprin	2		-	-	12.9
180	Arrestin domain-containing protein B	2		-	-	46.4
187	Kinase suppressor of Ras 2-like Protein	2		-	-	0.0
175	Receptor protein-tyrosine kinase	2		-	-	7.3
200	Uncharacterized protein	2		-	-	1.8
189	Caskin-1	2		-	-	0.0
182	Predicted protein	2		-	-	9.2
167	Sphingomyelin synthase-related protein 1	2		-	-	9.3
197	Receptor protein-tyrosine kinase	2		-	-	49.0
169	Protein Smaug homolog 2	2		-	-	0.0
190	Stromal interaction molecule 1	2		-	-	0.0
172	E74 like ETS transcription factor 3	2		-	-	6.6
191	Poly [ADP-ribose] polymerase	2		-	-	0.0
178	Mitogen-activated protein kinase kinase kinase 15	2		-	-	45.1
183	Epidermal growth factor receptor kinase substrate 8	2		-	-	0.0
177	Predicted protein	2		-	-	24.4
196	Predicted protein	2		-	-	41.2
194	AFR092Wp	2		-	-	1.3
171	sphingomyelin synthase-related protein 1	2		-	-	2.8
166	Uncharacterized protein	2		-	-	0.0
185	Caskin-1	2		-	-	0.0
198	Kinase, putative	2		-	-	46.0
195	GA repeat binding protein alpha homolog isoform X1	2		-	-	0.0
174	Ephrin receptor	2		-	-	0.0
188	Kinase suppressor of Ras 2	2		-	-	5.3
173	Ephrin receptor	2		-	-	0.0
232	Uncharacterized protein	1		-	-	0.0
207	Sec-23 interacting protein P125, putative	1		-	-	0.0
224	Uncharacterized protein	1		-	-	0.0
234	Uncharacterized protein	1		-	-	0.0
205	Uncharacterized protein	1		-	-	0.0
226	Eph receptor A4,-like	1		-	-	0.0
237	Kinesin-related protein 6	1		-	-	0.0
215	Uncharacterized protein	1		-	-	0.0
212	DDHD domain-containing 2	1		-	-	0.0
202	Uncharacterized protein	1		-	-	0.0
242	Uncharacterized protein	1		-	-	0.0
228	Uncharacterized protein	1		-	-	0.0
211	Predicted protein	1		-	-	0.0
218	Sphingomyelin synthase-related 1-like Protein	1		-	-	0.0
221	Uncharacterized protein	1		-	-	0.0
240	Predicted protein	1		-	-	0.0
230	Predicted protein	1		-	-	0.0
239	Uncharacterized protein	1		-	-	0.0
206	Uncharacterized protein	1		-	-	0.0
245	Uncharacterized protein	1		-	-	0.0
223	Uncharacterized protein	1		-	-	0.0
216	Predicted protein	1		-	-	0.0
225	Uncharacterized protein	1		-	-	0.0
222	transcription factor protein	1		-	-	0.0
217	Predicted protein	1		-	-	0.0
209	Predicted protein	1		-	-	0.0
233	Uncharacterized protein	1		-	-	0.0
204	Uncharacterized protein	1		-	-	0.0
236	Dual specificity protein kinase splA	1		-	-	0.0
227	EPH receptor A5	1		-	-	0.0
214	B cell linker	1		-	-	0.0
244	Uncharacterized protein	1		-	-	0.0
235	Uncharacterized protein	1		-	-	0.0
246	Predicted protein	1		-	-	0.0
229	Uncharacterized protein	1		-	-	0.0
210	Uncharacterized protein	1		-	-	0.0
213	Uncharacterized protein	1		-	-	0.0
243	Uncharacterized protein	1		-	-	0.0
203	Uncharacterized protein	1		-	-	0.0
238	Uncharacterized protein	1		-	-	0.0
219	Uncharacterized protein	1		-	-	0.0
220	Uncharacterized protein	1		-	-	0.0
208	Fli-1 proto-oncogene, ETS transcription factor a	1		-	-	0.0
241	Uncharacterized protein	1		-	-	0.0
201	Uncharacterized protein	1		-	-	0.0
231	Predicted protein	1		-	-	0.0