CATH Superfamily 1.10.1040.10
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".
FunFam 6: 3-hydroxyisobutyrate dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
12 |
P29266 (/ISS)
Q2HJD7 (/ISS)
Q5R5E7 (/ISS)
Q5R5E7 (/ISS)
Q83D20 (/ISS)
Q83D20 (/ISS)
Q889G7 (/ISS)
Q889G7 (/ISS)
Q889G7 (/ISS)
Q99L13 (/ISS)
(2 more) |
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
7 | P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) Q9SUC0 (/IDA) |
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
1 | Q99L13 (/ISO) |
|
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
|
1 | Q9I5I6 (/IDA) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9SUC0 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
6 | P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) |
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
6 | P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) |
|
Valine metabolic process GO:0006573
The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.
|
5 | Q83D20 (/ISS) Q83D20 (/ISS) Q889G7 (/ISS) Q889G7 (/ISS) Q889G7 (/ISS) |
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
5 | P29266 (/ISS) Q2HJD7 (/ISS) Q5R5E7 (/ISS) Q5R5E7 (/ISS) Q99L13 (/ISS) |
|
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
|
2 | Q9V8M5 (/ISS) Q9V8M5 (/ISS) |
|
Leucine metabolic process GO:0006551
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
|
1 | Q9SUC0 (/IMP) |
|
L-serine catabolic process GO:0006565
The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
|
1 | Q9I5I6 (/TAS) |
|
Valine metabolic process GO:0006573
The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.
|
1 | Q9SUC0 (/IMP) |
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
1 | Q99L13 (/ISO) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | Q9I5I6 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
6 | P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | Q99L13 (/HDA) Q9V8M5 (/HDA) Q9V8M5 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q9V8M5 (/ISS) Q9V8M5 (/ISS) |