CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.970 | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains |
Domain Context
CATH Clusters
Superfamily | 3.40.50.970 |
Functional Family | Transketolase |
Enzyme Information
2.2.1.1 |
Transketolase.
based on mapping to UniProt P23254
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
-!- Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO(2) and R-CHOH-CO-CH(2)OH. -!- The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor.
|
UniProtKB Entries (1)
P23254 |
TKT1_YEAST
Saccharomyces cerevisiae S288C
Transketolase 1
|
PDB Structure
PDB | 1TRK |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution.
J.Mol.Biol.
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