CATH Domain 1joyB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.287	Helix Hairpins
	1.10.287.130	Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain

Domain Context

CATH Clusters

Superfamily	1.10.287.130
Functional Family	Osmolarity two-component histidine kinase EnvZ

Enzyme Information

2.7.13.3

Histidine kinase.

based on mapping to UniProt P0AEJ4

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P0AEJ4

ENVZ_ECOLI

Escherichia coli K-12

Osmolarity sensor protein EnvZ

PDB Structure

PDB	1JOY
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ. Tomomori, C., Tanaka, T., Dutta, R., Park, H., Saha, S.K., Zhu, Y., Ishima, R., Liu, D., Tong, K.I., Kurokawa, H., Qian, H., Inouye, M., Ikura, M. Nat.Struct.Biol.