PDB Information

PDB5UFP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceHomo sapiens
Primary Citation
On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models.
Cho, H., Du, X., Rizzi, J.P., Liberzon, E., Chakraborty, A.A., Gao, W., Carvo, I., Signoretti, S., Bruick, R.K., Josey, J.A., Wallace, E.M., Kaelin, W.G.
Nature
HeaderTranscription
Released2017-01-05
Resolution1.900
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ufpA00 24 May, 2017 3.30.450.20 Assigned
5ufpB01 25 May, 2017 3.30.450.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q99814 EPAS1_HUMAN Homo sapiens Endothelial PAS domain-containing protein 1
P27540 ARNT_HUMAN Homo sapiens Aryl hydrocarbon receptor nuclear translocator