CATH Classification

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Hypoxia-inducible factor 1-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

P27540
ARNT_HUMAN
Homo sapiens
Aryl hydrocarbon receptor nuclear translocator

PDB Structure

PDB 5UFP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models.
Cho, H., Du, X., Rizzi, J.P., Liberzon, E., Chakraborty, A.A., Gao, W., Carvo, I., Signoretti, S., Bruick, R.K., Josey, J.A., Wallace, E.M., Kaelin, W.G.
Nature