CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.450 | Beta-Lactamase |
|
3.30.450.20 | PAS domain |
Domain Context
CATH Clusters
| Superfamily | PAS domain |
| Functional Family | Hypoxia-inducible factor 1-alpha isoform 1 |
Enzyme Information
UniProtKB Entries (1)
| Q99814 |
EPAS1_HUMAN
Homo sapiens
Endothelial PAS domain-containing protein 1
|
PDB Structure
| PDB | 5UFP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models.
Nature
|