PDB Information

PDB1Q32
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSaccharomyces cerevisiae
Primary Citation
Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison
He, X., van Waardenburg, R.C., Babaoglu, K., Price, A.C., Nitiss, K.C., Nitiss, J.L., Bjornsti, M.A., White, S.W.
J.Mol.Biol.
HeaderReplication,Transcription,Hydrolase
Released2003-07-28
Resolution2.030
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
1q32A01 05 Mar, 2006 3.30.870.10 Assigned
1q32A02 05 Mar, 2006 3.30.870.10 Assigned
1q32B01 08 Mar, 2006 3.30.870.10 Assigned
1q32B02 08 Mar, 2006 3.30.870.10 Assigned
1q32C01 08 Mar, 2006 3.30.870.10 Assigned
1q32C02 08 Mar, 2006 3.30.870.10 Assigned
1q32D01 08 Mar, 2006 3.30.870.10 Assigned
1q32D02 08 Mar, 2006 3.30.870.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P38319 TYDP1_YEAST Saccharomyces cerevisiae S288C Tyrosyl-DNA phosphodiesterase 1
P38319 TYDP1_YEAST Saccharomyces cerevisiae S288C Tyrosyl-DNA phosphodiesterase 1
P38319 TYDP1_YEAST Saccharomyces cerevisiae S288C Tyrosyl-DNA phosphodiesterase 1
P38319 TYDP1_YEAST Saccharomyces cerevisiae S288C Tyrosyl-DNA phosphodiesterase 1