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1 keywords

CATH Domain 1q32C01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.870 Endonuclease; Chain A
Homologous Superfamily 3.30.870.10 Endonuclease Chain A

Domain Context

CATH Clusters

Superfamily Endonuclease Chain A
Functional Family

Enzyme Information

3.1.4.-
Phosphoric diester hydrolases.
based on mapping to UniProt P38319

UniProtKB Entries (1)

P38319
TYDP1_YEAST
Saccharomyces cerevisiae S288C
Tyrosyl-DNA phosphodiesterase 1

PDB Structure

PDB 1Q32
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison
He, X., van Waardenburg, R.C., Babaoglu, K., Price, A.C., Nitiss, K.C., Nitiss, J.L., Bjornsti, M.A., White, S.W.
J.Mol.Biol.
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