CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.870 | Endonuclease; Chain A |
|
3.30.870.10 | Endonuclease Chain A |
Domain Context
CATH Clusters
| Superfamily | Endonuclease Chain A |
| Functional Family | Tyrosyl-DNA phosphodiesterase 1 |
Enzyme Information
| 3.1.4.- |
Phosphoric diester hydrolases.
based on mapping to UniProt P38319
|
UniProtKB Entries (1)
| P38319 |
TYDP1_YEAST
Saccharomyces cerevisiae S288C
Tyrosyl-DNA phosphodiesterase 1
|
PDB Structure
| PDB | 1Q32 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison
J.Mol.Biol.
|