The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Chloramphenicol acetyltransferase-like domain
".
FunFam 12: Non-ribosomal peptide synthetase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
7 | Q9I157 (/IMP) Q9I157 (/IMP) Q9I157 (/IMP) Q9I181 (/IMP) Q9I181 (/IMP) Q9I182 (/IMP) Q9I182 (/IMP) |
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
3 | Q9I157 (/IDA) Q9I157 (/IDA) Q9I157 (/IDA) |
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
2 | A0A0F7RHF8 (/ISS) A0A0F7RHF8 (/ISS) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | Q00869 (/IDA) |
|
Acid-amino acid ligase activity GO:0016881
Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
|
1 | Q00869 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pyoverdine biosynthetic process GO:0002049
The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
|
7 | Q9I157 (/IMP) Q9I157 (/IMP) Q9I157 (/IMP) Q9I181 (/IMP) Q9I181 (/IMP) Q9I182 (/IMP) Q9I182 (/IMP) |
|
Pyoverdine biosynthetic process GO:0002049
The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
|
3 | Q9I157 (/IDA) Q9I157 (/IDA) Q9I157 (/IDA) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
2 | Q51338 (/IMP) Q51338 (/IMP) |
|
Nonribosomal peptide biosynthetic process GO:0019184
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
|
2 | Q4KES9 (/IDA) Q4KES9 (/IDA) |
|
Nonribosomal peptide biosynthetic process GO:0019184
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
|
2 | A0A0F7RHF8 (/ISS) A0A0F7RHF8 (/ISS) |
|
Siderophore biosynthetic process GO:0019290
The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
|
2 | A0A0F7RHF8 (/ISS) A0A0F7RHF8 (/ISS) |
|
Toxin biosynthetic process GO:0009403
The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | Q0VZ70 (/IDA) |
|
Nonribosomal peptide biosynthetic process GO:0019184
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
|
1 | Q00869 (/TAS) |
|
Amino acid adenylylation by nonribosomal peptide synthase GO:0043042
Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.
|
1 | Q0VZ70 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
3 | Q10896 (/HDA) Q10896 (/HDA) Q10896 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q10896 (/HDA) Q10896 (/HDA) Q10896 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q10896 (/HDA) Q10896 (/HDA) Q10896 (/HDA) |
