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CATH Superfamily 6.10.180.10

Antitoxin ParD

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Antitoxin ParD
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Antitoxin ParD

According to the literature, structural domains which comprise this superfamily correspond to the structure of the antitoxin ParD, of the plasmid-encoded toxin-antitoxin (TA) system ParD-ParE.

ParD forms a homodimer and each monomer is comprised of a well-ordered N-terminal half and an unstructured C-terminal half. The former displays the ribbon-helix-helix (RHH) fold, a DNA-binding motif involved in auto-regulation. The latter on the other hand gains structure upon binding to its associated partner, the toxin ParE, and its responsible for its neutralisation PMID:17656583.

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
292 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 6
Taxonomy
Unique Species: 292
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