The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
IHF-like DNA-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: DNA-binding protein HU

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
383 P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI)
(373 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
383 P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI) P0ACF0 (/IPI)
(373 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
189 P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA)
(179 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
28 Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS)
(18 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
383 P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA)
(373 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
383 P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP)
(373 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
189 P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP) P0ACF0 (/IEP)
(179 more)
DNA packaging GO:0006323
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
28 Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS)
(18 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
383 P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA)
(373 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
189 P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA) P0ACF0 (/HDA)
(179 more)
HU-DNA complex GO:1990178
A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.
189 P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA) P0ACF0 (/IDA)
(179 more)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
28 Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS) Q9KQS9 (/ISS)
(18 more)
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